GO Annotations Graph

• Symbol: Ctnna1
• Name: catenin alpha 1
• ID: MGI:88274

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051015	actin filament binding	IDA	J:74778
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:155856
Molecular Function	GO:0008013	beta-catenin binding	IBA	J:265628
Molecular Function	GO:0045296	cadherin binding	ISO	J:164563
Molecular Function	GO:0045295	gamma-catenin binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:195204
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:61504
Molecular Function	GO:0005515	protein binding	IPI	J:183232
Molecular Function	GO:0005515	protein binding	IPI	J:204649
Molecular Function	GO:0005515	protein binding	IPI	J:87710
Molecular Function	GO:0005515	protein binding	IPI	J:87110
Molecular Function	GO:0005515	protein binding	IPI	J:35077
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005198	structural molecule activity	IEA	J:72247
Molecular Function	GO:0017166	vinculin binding	ISO	J:164563
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	IEA	J:72247
Cellular Component	GO:0005912	adherens junction	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:83082
Cellular Component	GO:0005912	adherens junction	IDA	J:143865
Cellular Component	GO:0005912	adherens junction	IDA	J:97223
Cellular Component	GO:0016342	catenin complex	ISO	J:164563
Cellular Component	GO:0016342	catenin complex	IBA	J:265628
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IEA	J:72247
Cellular Component	GO:0016600	flotillin complex	IDA	J:220503
Cellular Component	GO:0014704	intercalated disc	IDA	J:124009
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IDA	J:87902
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:35077
Cellular Component	GO:0005915	zonula adherens	IDA	J:65401
Biological Process	GO:0007015	actin filament organization	IEA	J:72247
Biological Process	GO:0043297	apical junction assembly	IMP	J:106707
Biological Process	GO:0043297	apical junction assembly	IMP	J:182219
Biological Process	GO:0006915	apoptotic process	IMP	J:106707
Biological Process	GO:0006915	apoptotic process	IMP	J:106707
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0048870	cell motility	IMP	J:182219
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0071681	cellular response to indole-3-methanol	ISO	J:164563
Biological Process	GO:0090136	epithelial cell-cell adhesion	IMP	J:182219
Biological Process	GO:0007163	establishment or maintenance of cell polarity	IMP	J:106707
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:182219
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:182219
Biological Process	GO:0016264	gap junction assembly	ISO	J:155856
Biological Process	GO:0007229	integrin-mediated signaling pathway	IMP	J:182219
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:106707
Biological Process	GO:2000146	negative regulation of cell motility	IMP	J:182219
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:182219
Biological Process	GO:2001045	negative regulation of integrin-mediated signaling pathway	IMP	J:182219
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	IMP	J:106707
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	IGI	J:106707
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	IMP	J:169049
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:106707
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:106707
Biological Process	GO:0007405	neuroblast proliferation	IGI	J:106707
Biological Process	GO:0007405	neuroblast proliferation	IGI	J:106707
Biological Process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:182219
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IGI	J:106707
Biological Process	GO:0008104	protein localization	IMP	J:182219
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:127452
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:106707
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:106707