GO Annotations Graph

• Symbol: Bcr
• Name: BCR activator of RhoGEF and GTPase
• ID: MGI:88141

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:118168
Molecular Function	GO:0005096	GTPase activator activity	IGI	J:153997
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:118168
Molecular Function	GO:0005096	GTPase activator activity	TAS	J:72425
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:216285
Molecular Function	GO:0005515	protein binding	IPI	J:118143
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:118168
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:165475
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:165475
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:118168
Cellular Component	GO:0014069	postsynaptic density	IDA	J:216285
Cellular Component	GO:0099092	postsynaptic density, intracellular component	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:194542
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:165475
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:165475
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0030036	actin cytoskeleton organization	IGI	J:118168
Biological Process	GO:0030036	actin cytoskeleton organization	IGI	J:118168
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:164563
Biological Process	GO:0007420	brain development	IGI	J:72425
Biological Process	GO:0016477	cell migration	IGI	J:118168
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:23804
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:23804
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:118168
Biological Process	GO:0048041	focal adhesion assembly	ISO	J:164563
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:23804
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:108010
Biological Process	GO:0065002	intracellular protein transmembrane transport	IMP	J:23804
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0030216	keratinocyte differentiation	ISO	J:164563
Biological Process	GO:1905517	macrophage migration	IGI	J:118168
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:165475
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:165475
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:165475
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:165475
Biological Process	GO:0060313	negative regulation of blood vessel remodeling	IMP	J:195022
Biological Process	GO:0002692	negative regulation of cellular extravasation	IMP	J:195022
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:153997
Biological Process	GO:1905522	negative regulation of macrophage migration	IGI	J:118168
Biological Process	GO:0043314	negative regulation of neutrophil degranulation	IGI	J:153997
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IMP	J:23804
Biological Process	GO:0060268	negative regulation of respiratory burst	IMP	J:23804
Biological Process	GO:0050885	neuromuscular process controlling balance	IGI	J:108010
Biological Process	GO:0043312	neutrophil degranulation	IGI	J:153997
Biological Process	GO:0006909	phagocytosis	IGI	J:118168
Biological Process	GO:0006909	phagocytosis	IGI	J:118168
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	IEA	J:72247
Biological Process	GO:0050766	positive regulation of phagocytosis	IGI	J:118168
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:74002
Biological Process	GO:0051171	regulation of nitrogen compound metabolic process	IMP	J:23804
Biological Process	GO:0035023	regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0043114	regulation of vascular permeability	IMP	J:195022
Biological Process	GO:0003014	renal system process	IMP	J:23804
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:153997
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007264	small GTPase mediated signal transduction	ISO	J:164563