Alpl GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Alpl
alkaline phosphatase, liver/bone/kidney
MGI:87983

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004035	alkaline phosphatase activity	ISO	J:155856
Molecular Function	GO:0004035	alkaline phosphatase activity	ISO	J:164563
Molecular Function	GO:0004035	alkaline phosphatase activity	IBA	J:265628
Molecular Function	GO:0004035	alkaline phosphatase activity	IDA	J:120537
Molecular Function	GO:0004035	alkaline phosphatase activity	IDA	J:21480
Molecular Function	GO:0004035	alkaline phosphatase activity	IDA	J:130731
Molecular Function	GO:0004035	alkaline phosphatase activity	ISO	J:11608
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0050187	phosphoamidase activity	IDA	J:306607
Molecular Function	GO:0052732	phosphoethanolamine phosphatase activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0033883	pyridoxal phosphatase activity	ISO	J:164563
Molecular Function	GO:0016462	pyrophosphatase activity	IDA	J:314086
Molecular Function	GO:0016462	pyrophosphatase activity	IMP	J:179862
Molecular Function	GO:0016462	pyrophosphatase activity	ISO	J:73065
Cellular Component	GO:0031012	extracellular matrix	IDA	J:179862
Cellular Component	GO:0065010	extracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0065010	extracellular membrane-bounded organelle	IDA	J:179862
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005758	mitochondrial intermembrane space	IDA	J:306607
Cellular Component	GO:0031966	mitochondrial membrane	IDA	J:306607
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:21480
Cellular Component	GO:0005886	plasma membrane	IDA	J:120537
Biological Process	GO:0031214	biomineral tissue development	IEA	J:60000
Biological Process	GO:0030282	bone mineralization	IMP	J:314754
Biological Process	GO:0030282	bone mineralization	IMP	J:78130
Biological Process	GO:0030282	bone mineralization	IMP	J:314565
Biological Process	GO:0030282	bone mineralization	IMP	J:39015
Biological Process	GO:0030282	bone mineralization	IMP	J:173678
Biological Process	GO:0030282	bone mineralization	IMP	J:88444
Biological Process	GO:0030282	bone mineralization	IMP	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:98814
Biological Process	GO:0030282	bone mineralization	IMP	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:98814
Biological Process	GO:0030282	bone mineralization	IMP	J:98814
Biological Process	GO:0030282	bone mineralization	IMP	J:77731
Biological Process	GO:0030282	bone mineralization	IMP	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:77731
Biological Process	GO:0030282	bone mineralization	IMP	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:77731
Biological Process	GO:0030282	bone mineralization	IGI	J:77731
Biological Process	GO:0030282	bone mineralization	IMP	J:77731
Biological Process	GO:0030282	bone mineralization	IMP	J:98814
Biological Process	GO:0055074	calcium ion homeostasis	IDA	J:173773
Biological Process	GO:0055074	calcium ion homeostasis	ISO	J:252837
Biological Process	GO:0055074	calcium ion homeostasis	IMP	J:252837
Biological Process	GO:0019725	cellular homeostasis	IMP	J:77731
Biological Process	GO:0019725	cellular homeostasis	IGI	J:77731
Biological Process	GO:0019725	cellular homeostasis	IMP	J:77731
Biological Process	GO:0019725	cellular homeostasis	IGI	J:77731
Biological Process	GO:0071407	cellular response to organic cyclic compound	IDA	J:97016
Biological Process	GO:0016311	dephosphorylation	IBA	J:265628
Biological Process	GO:0003006	developmental process involved in reproduction	IGI	J:122954
Biological Process	GO:0001958	endochondral ossification	IMP	J:173678
Biological Process	GO:0140651	futile creatine cycle	IDA	J:306607
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	IMP	J:173773
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	IMP	J:173773
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	IDA	J:173773
Biological Process	GO:0055062	phosphate ion homeostasis	IMP	J:77731
Biological Process	GO:0055062	phosphate ion homeostasis	IGI	J:77731
Biological Process	GO:0055062	phosphate ion homeostasis	IDA	J:173773
Biological Process	GO:0055062	phosphate ion homeostasis	IMP	J:173773
Biological Process	GO:0055062	phosphate ion homeostasis	IMP	J:77731
Biological Process	GO:0055062	phosphate ion homeostasis	IGI	J:77731
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IDA	J:306607
Biological Process	GO:0042822	pyridoxal phosphate metabolic process	IDA	J:28394
Biological Process	GO:0046677	response to antibiotic	IDA	J:11608
Biological Process	GO:0051384	response to glucocorticoid	ISO	J:155856
Biological Process	GO:1904383	response to sodium phosphate	IDA	J:201223
Biological Process	GO:1904383	response to sodium phosphate	IMP	J:77731
Biological Process	GO:1904383	response to sodium phosphate	IGI	J:77731
Biological Process	GO:0034516	response to vitamin B6	IMP	J:77731
Biological Process	GO:0034516	response to vitamin B6	IGI	J:77731

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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