GO Annotations Graph

• Symbol: Actc1
• Name: actin, alpha, cardiac muscle 1
• ID: MGI:87905

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000146	microfilament motor activity	ISO	J:164563
Molecular Function	GO:0017022	myosin binding	ISO	J:164563
Molecular Function	GO:0017022	myosin binding	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:192758
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0005884	actin filament	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:206458
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:206458
Cellular Component	GO:0031674	I band	IDA	J:112534
Cellular Component	GO:0030017	sarcomere	ISO	J:164563
Cellular Component	GO:0030017	sarcomere	IBA	J:265628
Cellular Component	GO:0045202	synapse	EXP	J:206458
Cellular Component	GO:0045202	synapse	IDA	J:206458
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0030048	actin filament-based movement	ISO	J:164563
Biological Process	GO:0070252	actin-mediated cell contraction	IMP	J:193444
Biological Process	GO:0033275	actin-myosin filament sliding	ISO	J:164563
Biological Process	GO:0033275	actin-myosin filament sliding	IBA	J:265628
Biological Process	GO:0031032	actomyosin structure organization	IMP	J:102007
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:155856
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	IMP	J:102007
Biological Process	GO:0055003	cardiac myofibril assembly	IMP	J:40165
Biological Process	GO:0060047	heart contraction	ISO	J:164563
Biological Process	GO:0060047	heart contraction	IBA	J:265628
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:102007
Biological Process	GO:0030240	skeletal muscle thin filament assembly	IMP	J:40165