GO Annotations Graph

• Symbol: Akap6
• Name: A kinase anchor protein 6
• ID: MGI:3050566

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008179	adenylate cyclase binding	ISO	J:155856
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:197247
Molecular Function	GO:0051018	protein kinase A binding	ISO	J:155856
Molecular Function	GO:0051018	protein kinase A binding	IBA	J:265628
Molecular Function	GO:0051018	protein kinase A binding	ISO	J:73065
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	ISO	J:155856
Molecular Function	GO:0051721	protein phosphatase 2A binding	ISO	J:155856
Molecular Function	GO:0043495	protein-membrane adaptor activity	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Cellular Component	GO:0034704	calcium channel complex	ISO	J:164563
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0014701	junctional sarcoplasmic reticulum membrane	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	ISO	J:73065
Cellular Component	GO:0031965	nuclear membrane	ISO	J:155856
Cellular Component	GO:0031965	nuclear membrane	IDA	J:159250
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:198914
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0016529	sarcoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0016529	sarcoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0016529	sarcoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0016529	sarcoplasmic reticulum	ISO	J:73065
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Biological Process	GO:0071320	cellular response to cAMP	ISO	J:164563
Biological Process	GO:0071345	cellular response to cytokine stimulus	ISO	J:155856
Biological Process	GO:0071872	cellular response to epinephrine stimulus	ISO	J:155856
Biological Process	GO:0007194	negative regulation of adenylate cyclase activity	ISO	J:155856
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	ISO	J:155856
Biological Process	GO:2000481	positive regulation of cAMP-dependent protein kinase activity	ISO	J:155856
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:155856
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:1902261	positive regulation of delayed rectifier potassium channel activity	ISO	J:164563
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	ISO	J:155856
Biological Process	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	ISO	J:155856
Biological Process	GO:0045727	positive regulation of translation	ISO	J:155856
Biological Process	GO:0031503	protein-containing complex localization	ISO	J:155856
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction	ISO	J:155856
Biological Process	GO:0060306	regulation of membrane repolarization	ISO	J:164563
Biological Process	GO:0010738	regulation of protein kinase A signaling	ISO	J:155856
Biological Process	GO:1901897	regulation of relaxation of cardiac muscle	ISO	J:155856