GO Annotations Graph

• Symbol: Cd226
• Name: CD226 antigen
• ID: MGI:3039602

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:322383
Molecular Function	GO:0005515	protein binding	IPI	J:97476
Molecular Function	GO:0005515	protein binding	IPI	J:97476
Molecular Function	GO:0005515	protein binding	IPI	J:175415
Molecular Function	GO:0005515	protein binding	IPI	J:209990
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:151768
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0001816	cytokine production	IBA	J:265628
Biological Process	GO:0001816	cytokine production	IDA	J:97476
Biological Process	GO:0002370	natural killer cell cytokine production	IMP	J:209990
Biological Process	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	ISO	J:164563
Biological Process	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	IBA	J:265628
Biological Process	GO:0002891	positive regulation of immunoglobulin mediated immune response	ISO	J:164563
Biological Process	GO:0002891	positive regulation of immunoglobulin mediated immune response	IBA	J:265628
Biological Process	GO:0033005	positive regulation of mast cell activation	ISO	J:164563
Biological Process	GO:0033005	positive regulation of mast cell activation	IBA	J:265628
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	IBA	J:265628
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	IMP	J:209990
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	ISO	J:164563
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	ISO	J:164563
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IBA	J:265628
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	IBA	J:265628
Biological Process	GO:0032729	positive regulation of type II interferon production	IBA	J:265628
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:209990