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GO Annotations Graph
Symbol
Name
ID
Nlrc4
NLR family, CARD domain containing 4
MGI:3036243

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0004869cysteine-type endopeptidase inhibitor activityIBAJ:161428
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0004842ubiquitin-protein transferase activityIBAJ:161428
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005829cytosolIDAJ:189256
Cellular ComponentGO:0072557IPAF inflammasome complexIDAJ:189256
Cellular ComponentGO:0072557IPAF inflammasome complexIDAJ:176197
Cellular ComponentGO:0005634nucleusIBAJ:161428
Cellular ComponentGO:0005876spindle microtubuleIBAJ:161428
Biological ProcessGO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic processISOJ:164563
Biological ProcessGO:0002218activation of innate immune responseIMPJ:112671
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0042742defense response to bacteriumIMPJ:176197
Biological ProcessGO:0042742defense response to bacteriumIMPJ:185371
Biological ProcessGO:0042742defense response to bacteriumISOJ:164563
Biological ProcessGO:0042742defense response to bacteriumIMPJ:112671
Biological ProcessGO:0042742defense response to bacteriumIMPJ:112670
Biological ProcessGO:0042742defense response to bacteriumIMPJ:189256
Biological ProcessGO:0016045detection of bacteriumISOJ:164563
Biological ProcessGO:0016045detection of bacteriumIMPJ:189256
Biological ProcessGO:0002376immune system processIEAJ:60000
Biological ProcessGO:0006954inflammatory responseIMPJ:189256
Biological ProcessGO:0006954inflammatory responseIMPJ:185371
Biological ProcessGO:0006954inflammatory responseIMPJ:176197
Biological ProcessGO:0006954inflammatory responseIMPJ:112671
Biological ProcessGO:0006954inflammatory responseIMPJ:112670
Biological ProcessGO:0006954inflammatory responseIMPJ:91292
Biological ProcessGO:1990001inhibition of cysteine-type endopeptidase activity involved in apoptotic processIBAJ:161428
Biological ProcessGO:0045087innate immune responseIEAJ:60000
Biological ProcessGO:0050702interleukin-1 beta secretionIMPJ:185371
Biological ProcessGO:0050702interleukin-1 beta secretionIMPJ:112671
Biological ProcessGO:0050702interleukin-1 beta secretionIMPJ:112670
Biological ProcessGO:0050702interleukin-1 beta secretionISOJ:164563
Biological ProcessGO:0090307mitotic spindle assemblyIBAJ:161428
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:164563
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityISOJ:164563
Biological ProcessGO:0051260protein homooligomerizationIDAJ:176197
Biological ProcessGO:0070269pyroptosisIMPJ:185371
Biological ProcessGO:0070269pyroptosisIMPJ:189256
Biological ProcessGO:0070269pyroptosisIMPJ:176197
Biological ProcessGO:0070269pyroptosisIMPJ:112671
Biological ProcessGO:0070269pyroptosisIMPJ:112670
Biological ProcessGO:0042981regulation of apoptotic processIMPJ:91292
Biological ProcessGO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic processIMPJ:91292
Biological ProcessGO:0009966regulation of signal transductionIBAJ:161428


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/13/2022
MGI 6.21
The Jackson Laboratory