GO Annotations Graph

• Symbol: Plekhg5
• Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
• ID: MGI:2652860

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IDA	J:112471
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Molecular Function	GO:0005515	protein binding	IPI	J:112471
Molecular Function	GO:0005515	protein binding	IPI	J:112471
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:200496
Cellular Component	GO:0005737	cytoplasm	IDA	J:200496
Cellular Component	GO:0005737	cytoplasm	IDA	J:112471
Cellular Component	GO:0030139	endocytic vesicle	IDA	J:200496
Cellular Component	GO:0030139	endocytic vesicle	IBA	J:265628
Cellular Component	GO:0030027	lamellipodium	IDA	J:200496
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:112471
Cellular Component	GO:0098793	presynapse	IDA	J:252982
Cellular Component	GO:0045202	synapse	IDA	J:252982
Biological Process	GO:0035767	endothelial cell chemotaxis	IMP	J:200496
Biological Process	GO:0043542	endothelial cell migration	IBA	J:265628
Biological Process	GO:0043542	endothelial cell migration	IDA	J:112471
Biological Process	GO:0140251	regulation protein catabolic process at presynapse	IDA	J:252982
Biological Process	GO:0140251	regulation protein catabolic process at presynapse	IDA	J:252982
Biological Process	GO:0140251	regulation protein catabolic process at presynapse	IMP	J:252982
Biological Process	GO:0140251	regulation protein catabolic process at presynapse	IDA	J:252982
Biological Process	GO:0140251	regulation protein catabolic process at presynapse	IDA	J:252982
Biological Process	GO:0140251	regulation protein catabolic process at presynapse	IPI	J:252982
Biological Process	GO:0007266	Rho protein signal transduction	IBA	J:265628