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GO Annotations Graph
Symbol
Name
ID
A2m
alpha-2-macroglobulin
MGI:2449119

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0048403brain-derived neurotrophic factor bindingISOJ:155856
Molecular FunctionGO:0048306calcium-dependent protein bindingISOJ:164563
Molecular FunctionGO:0004866endopeptidase inhibitor activityISOJ:155856
Molecular FunctionGO:0019899enzyme bindingISOJ:164563
Molecular FunctionGO:0019838growth factor bindingISOJ:164563
Molecular FunctionGO:0019966interleukin-1 bindingISOJ:164563
Molecular FunctionGO:0019959interleukin-8 bindingISOJ:164563
Molecular FunctionGO:0048406nerve growth factor bindingISOJ:155856
Molecular FunctionGO:0030414peptidase inhibitor activityTASJ:3922
Molecular FunctionGO:0002020protease bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:126954
Molecular FunctionGO:0042803protein homodimerization activityISOJ:155856
Molecular FunctionGO:0005102receptor bindingISOJ:164563
Molecular FunctionGO:0004867serine-type endopeptidase inhibitor activityISOJ:164563
Molecular FunctionGO:0043120tumor necrosis factor bindingISOJ:164563
Cellular ComponentGO:0072562blood microparticleISOJ:164563
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005576extracellular regionIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Biological ProcessGO:0007565female pregnancyIEAJ:60000
Biological ProcessGO:0001869negative regulation of complement activation, lectin pathwayISOJ:164563
Biological ProcessGO:0010951negative regulation of endopeptidase activityISOJ:164563
Biological ProcessGO:0010466negative regulation of peptidase activityIEAJ:60000
Biological ProcessGO:0048863stem cell differentiationIDAJ:154112


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory