GO Annotations Graph

• Symbol: Pik3c3
• Name: phosphatidylinositol 3-kinase catalytic subunit type 3
• ID: MGI:2445019

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Wed Mar 2 12:11:24 2016.

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	IBA	J:161428
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	ISO	J:164563
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0035004	phosphatidylinositol 3-kinase activity	ISO	J:155856
Molecular Function	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:185616
Molecular Function	GO:0005515	protein binding	IPI	J:220500
Molecular Function	GO:0005515	protein binding	IPI	J:219056
Molecular Function	GO:0005515	protein binding	IPI	J:202483
Molecular Function	GO:0004672	protein kinase activity	IMP	J:93872
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	IBA	J:161428
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	IBA	J:161428
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:185616
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	IDA	J:219056
Cellular Component	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	IBA	J:161428
Cellular Component	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	IBA	J:161428
Cellular Component	GO:0000407	pre-autophagosomal structure	IBA	J:161428
Biological Process	GO:0000045	autophagosome assembly	ISO	J:155856
Biological Process	GO:0000045	autophagosome assembly	IBA	J:161428
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0042149	cellular response to glucose starvation	IDA	J:219056
Biological Process	GO:0000910	cytokinesis	ISO	J:164563
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0006897	endocytosis	IBA	J:161428
Biological Process	GO:0016197	endosomal transport	IBA	J:161428
Biological Process	GO:0007032	endosome organization	ISO	J:155856
Biological Process	GO:0016236	macroautophagy	IMP	J:219056
Biological Process	GO:0016236	macroautophagy	IMP	J:219972
Biological Process	GO:0030242	pexophagy	IBA	J:161428
Biological Process	GO:0046854	phosphatidylinositol phosphorylation	IEA	J:72247
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	ISO	J:155856
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	ISO	J:155856
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0006468	protein phosphorylation	IMP	J:93872
Biological Process	GO:0016485	protein processing	ISO	J:155856
Biological Process	GO:0032465	regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0050708	regulation of protein secretion	ISO	J:155856

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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