GO Annotations Graph

• Symbol: Mbtps2
• Name: membrane-bound transcription factor peptidase, site 2
• ID: MGI:2444506

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004222	metalloendopeptidase activity	ISO	J:164563
Molecular Function	GO:0004222	metalloendopeptidase activity	TAS	Reactome:R-MMU-6784684
Molecular Function	GO:0004222	metalloendopeptidase activity	TAS	Reactome:R-MMU-8874239
Molecular Function	GO:0004222	metalloendopeptidase activity	TAS	Reactome:R-MMU-8874285
Molecular Function	GO:0004222	metalloendopeptidase activity	TAS	Reactome:R-MMU-8874364
Molecular Function	GO:0004222	metalloendopeptidase activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAS	Reactome:R-MMU-6784684
Cellular Component	GO:0000139	Golgi membrane	TAS	Reactome:R-MMU-8874239
Cellular Component	GO:0000139	Golgi membrane	TAS	Reactome:R-MMU-8874285
Cellular Component	GO:0000139	Golgi membrane	TAS	Reactome:R-MMU-8874364
Biological Process	GO:0070977	bone maturation	ISO	J:164563
Biological Process	GO:0031293	membrane protein intracellular domain proteolysis	ISO	J:164563
Biological Process	GO:0031293	membrane protein intracellular domain proteolysis	IBA	J:265628
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IBA	J:265628
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	IBA	J:265628
Biological Process	GO:0051604	protein maturation	ISO	J:164563
Biological Process	GO:1905897	regulation of response to endoplasmic reticulum stress	IBA	J:265628