GO Annotations Graph

• Symbol: Osbpl8
• Name: oxysterol binding protein-like 8
• ID: MGI:2443807

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015485	cholesterol binding	ISO	J:164563
Molecular Function	GO:0015485	cholesterol binding	IBA	J:265628
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0008289	lipid binding	IEA	J:72247
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	ISO	J:164563
Molecular Function	GO:0001786	phosphatidylserine binding	ISO	J:164563
Molecular Function	GO:0140343	phosphatidylserine transfer activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:176266
Molecular Function	GO:0015248	sterol transporter activity	IBA	J:265628
Cellular Component	GO:0032541	cortical endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0031965	nuclear membrane	IMP	J:187070
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0032148	activation of protein kinase B activity	IMP	J:222138
Biological Process	GO:0045444	fat cell differentiation	ISO	J:164563
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0030336	negative regulation of cell migration	IMP	J:176266
Biological Process	GO:0010891	negative regulation of sequestering of triglyceride	ISO	J:164563
Biological Process	GO:0015914	phospholipid transport	ISO	J:164563
Biological Process	GO:0046326	positive regulation of glucose import	IMP	J:222138
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	IDA	J:222138
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	IMP	J:176266
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	IMP	J:222138
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	IMP	J:176266
Biological Process	GO:0090204	protein localization to nuclear pore	IMP	J:176266