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GO Annotations Graph
Symbol
Name
ID
Tpcn2
two pore segment channel 2
MGI:2385297

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005262calcium channel activityIEAJ:60000
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0005216ion channel activityIEAJ:72247
Molecular FunctionGO:0072345NAADP-sensitive calcium-release channel activityIDAJ:175352
Molecular FunctionGO:0072345NAADP-sensitive calcium-release channel activityISOJ:164563
Molecular FunctionGO:0072345NAADP-sensitive calcium-release channel activityIMPJ:175340
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0005245voltage-gated calcium channel activityIMPJ:175340
Molecular FunctionGO:0005244voltage-gated ion channel activityIEAJ:60000
Cellular ComponentGO:0010008endosome membraneISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005765lysosomal membraneIDAJ:175352
Cellular ComponentGO:0005765lysosomal membraneISOJ:164563
Cellular ComponentGO:0005764lysosomeISOJ:164563
Cellular ComponentGO:0005764lysosomeIDAJ:175340
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneIBAJ:161428
Biological ProcessGO:0070588calcium ion transmembrane transportIEAJ:60000
Biological ProcessGO:0006816calcium ion transportIEAJ:60000
Biological ProcessGO:0019722calcium-mediated signalingISOJ:164563
Biological ProcessGO:0006874cellular calcium ion homeostasisISOJ:164563
Biological ProcessGO:0006811ion transportIEAJ:60000
Biological ProcessGO:0006811ion transportIEAJ:72247
Biological ProcessGO:0007040lysosome organizationISOJ:164563
Biological ProcessGO:0086010membrane depolarization during action potentialIBAJ:161428
Biological ProcessGO:0010506regulation of autophagyISOJ:164563
Biological ProcessGO:0034765regulation of ion transmembrane transportIEAJ:60000
Biological ProcessGO:0051209release of sequestered calcium ion into cytosolIMPJ:175340
Biological ProcessGO:0006939smooth muscle contractionIMPJ:165894
Biological ProcessGO:0055085transmembrane transportIEAJ:72247
Biological ProcessGO:0006810transportIEAJ:60000


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory