GO Annotations Graph

• Symbol: Spns2
• Name: SPNS lysolipid transporter 2, sphingosine-1-phosphate
• ID: MGI:2384936

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046624	sphingolipid transporter activity	ISO	J:164563
Molecular Function	GO:0046624	sphingolipid transporter activity	IDA	J:319686
Molecular Function	GO:0046624	sphingolipid transporter activity	IDA	J:196347
Molecular Function	GO:0046624	sphingolipid transporter activity	IDA	J:319866
Molecular Function	GO:0046624	sphingolipid transporter activity	IBA	J:265628
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0001782	B cell homeostasis	IMP	J:184558
Biological Process	GO:0001782	B cell homeostasis	IMP	J:184558
Biological Process	GO:0001782	B cell homeostasis	IMP	J:188933
Biological Process	GO:0001782	B cell homeostasis	IMP	J:188933
Biological Process	GO:0060348	bone development	IMP	J:188142
Biological Process	GO:0006869	lipid transport	ISO	J:164563
Biological Process	GO:0006869	lipid transport	IBA	J:265628
Biological Process	GO:0048535	lymph node development	IMP	J:196984
Biological Process	GO:0002260	lymphocyte homeostasis	IMP	J:196984
Biological Process	GO:0072676	lymphocyte migration	IMP	J:184558
Biological Process	GO:0072676	lymphocyte migration	IMP	J:184558
Biological Process	GO:0048073	regulation of eye pigmentation	IMP	J:188933
Biological Process	GO:0002920	regulation of humoral immune response	IDA	J:319866
Biological Process	GO:0002920	regulation of humoral immune response	IMP	J:188933
Biological Process	GO:2000404	regulation of T cell migration	IDA	J:319866
Biological Process	GO:0007605	sensory perception of sound	IMP	J:228852
Biological Process	GO:0006665	sphingolipid metabolic process	IMP	J:196984
Biological Process	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	IDA	J:196347
Biological Process	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	IDA	J:319866
Biological Process	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	IDA	J:319686
Biological Process	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	IBA	J:265628
Biological Process	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	IMP	J:184558
Biological Process	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	IMP	J:196984
Biological Process	GO:0043029	T cell homeostasis	IMP	J:188933
Biological Process	GO:0043029	T cell homeostasis	IMP	J:188933
Biological Process	GO:0043029	T cell homeostasis	IMP	J:184558
Biological Process	GO:0043029	T cell homeostasis	IMP	J:184558
Biological Process	GO:0043029	T cell homeostasis	IMP	J:184558
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247