GO Annotations Graph

• Symbol: Plxna4
• Name: plexin A4
• ID: MGI:2179061

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:163378
Molecular Function	GO:0005515	protein binding	IPI	J:98330
Molecular Function	GO:0005515	protein binding	IPI	J:98330
Molecular Function	GO:0017154	semaphorin receptor activity	IBA	J:265628
Molecular Function	GO:0017154	semaphorin receptor activity	IGI	J:82114
Cellular Component	GO:0150053	cerebellar climbing fiber to Purkinje cell synapse	IDA	J:211258
Cellular Component	GO:0150053	cerebellar climbing fiber to Purkinje cell synapse	IMP	J:211258
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2045917
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9615031
Cellular Component	GO:0005886	plasma membrane	ISS	J:82114
Cellular Component	GO:0002116	semaphorin receptor complex	IBA	J:265628
Biological Process	GO:0021960	anterior commissure morphogenesis	IMP	J:98330
Biological Process	GO:0007411	axon guidance	IMP	J:98330
Biological Process	GO:0021785	branchiomotor neuron axon guidance	IMP	J:142715
Biological Process	GO:0021793	chemorepulsion of branchiomotor axon	IMP	J:98330
Biological Process	GO:0021602	cranial nerve morphogenesis	IMP	J:98330
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:274700
Biological Process	GO:0021610	facial nerve morphogenesis	IMP	J:98330
Biological Process	GO:0021612	facial nerve structural organization	IMP	J:142715
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	IMP	J:98330
Biological Process	GO:0099558	maintenance of synapse structure	IMP	J:211258
Biological Process	GO:0099558	maintenance of synapse structure	IDA	J:211258
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:142715
Biological Process	GO:0007162	negative regulation of cell adhesion	IBA	J:265628
Biological Process	GO:0007399	nervous system development	IGI	J:82114
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:98330
Biological Process	GO:0050772	positive regulation of axonogenesis	IBA	J:265628
Biological Process	GO:0021784	postganglionic parasympathetic fiber development	IMP	J:98330
Biological Process	GO:0048841	regulation of axon extension involved in axon guidance	IMP	J:98330
Biological Process	GO:0030334	regulation of cell migration	IBA	J:265628
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0050923	regulation of negative chemotaxis	IMP	J:98330
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IGI	J:82114
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IMP	J:98330
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IGI	J:82114
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	IMP	J:142715
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0048485	sympathetic nervous system development	IMP	J:98330
Biological Process	GO:0097492	sympathetic neuron axon guidance	IGI	J:274700
Biological Process	GO:0021636	trigeminal nerve morphogenesis	IMP	J:98330
Biological Process	GO:0021637	trigeminal nerve structural organization	IMP	J:142715
Biological Process	GO:0021644	vagus nerve morphogenesis	IMP	J:98330