GO Annotations Graph

• Symbol: Arhgdia
• Name: Rho GDP dissociation inhibitor alpha
• ID: MGI:2178103

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005504	fatty acid binding	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	IEA	J:60000
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:204642
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:205847
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0005094	Rho GDP-dissociation inhibitor activity	IBA	J:265628
Molecular Function	GO:0005094	Rho GDP-dissociation inhibitor activity	IDA	J:89351
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0001772	immunological synapse	IDA	J:94032
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:219617
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:219617
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:142806
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:142806
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:142806
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0071260	cellular response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:155856
Biological Process	GO:2000249	regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	ISO	J:155856
Biological Process	GO:0032880	regulation of protein localization	IDA	J:36812
Biological Process	GO:0035023	regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IDA	J:142806
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IMP	J:142806
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IDA	J:142806
Biological Process	GO:0007266	Rho protein signal transduction	IBA	J:265628
Biological Process	GO:0007266	Rho protein signal transduction	IDA	J:89351
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IMP	J:204642