GO Annotations Graph

• Symbol: Hps1
• Name: HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
• ID: MGI:2177763

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0046983	protein dimerization activity	ISO	J:164563
Cellular Component	GO:0031085	BLOC-3 complex	ISO	J:164563
Cellular Component	GO:0031085	BLOC-3 complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:75144
Biological Process	GO:0007596	blood coagulation	IMP	J:7327
Biological Process	GO:0000902	cell morphogenesis	IGI	J:85431
Biological Process	GO:0048069	eye pigmentation	IMP	J:166679
Biological Process	GO:0010467	gene expression	IMP	J:286751
Biological Process	GO:0006954	inflammatory response	IGI	J:85431
Biological Process	GO:0046907	intracellular transport	NAS	J:320062
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:287084
Biological Process	GO:0030324	lung development	IGI	J:85431
Biological Process	GO:0060425	lung morphogenesis	IGI	J:85431
Biological Process	GO:0007040	lysosome organization	IMP	J:287084
Biological Process	GO:0030318	melanocyte differentiation	IMP	J:75144
Biological Process	GO:1903232	melanosome assembly	NAS	J:320062
Biological Process	GO:1903232	melanosome assembly	ISO	J:164563
Biological Process	GO:1903232	melanosome assembly	IBA	J:265628
Biological Process	GO:0006996	organelle organization	IMP	J:75144
Biological Process	GO:0043473	pigmentation	IMP	J:29467
Biological Process	GO:0043473	pigmentation	IMP	J:6801
Biological Process	GO:0060155	platelet dense granule organization	NAS	J:235260
Biological Process	GO:0032816	positive regulation of natural killer cell activation	IMP	J:6801
Biological Process	GO:0003016	respiratory system process	IGI	J:85431
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:166679
Biological Process	GO:0033299	secretion of lysosomal enzymes	IMP	J:6801
Biological Process	GO:0007338	single fertilization	IMP	J:287084
Biological Process	GO:0007283	spermatogenesis	IMP	J:287084
Biological Process	GO:0016192	vesicle-mediated transport	IEA	J:72247