GO Annotations Graph

• Symbol: Pja2
• Name: praja ring finger ubiquitin ligase 2
• ID: MGI:2159342

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:212985
Molecular Function	GO:0005515	protein binding	IPI	J:77266
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	ISO	J:164563
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0045111	intermediate filament cytoskeleton	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0035329	hippo signaling	IEA	J:72247
Biological Process	GO:0006954	inflammatory response	ISO	J:164563
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0007616	long-term memory	ISO	J:155856
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	ISO	J:164563
Biological Process	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0043030	regulation of macrophage activation	ISO	J:164563
Biological Process	GO:0010738	regulation of protein kinase A signaling	ISO	J:164563
Biological Process	GO:0010738	regulation of protein kinase A signaling	ISO	J:155856
Biological Process	GO:0010738	regulation of protein kinase A signaling	IBA	J:265628