GO Annotations Graph

• Symbol: Myh7
• Name: myosin, heavy polypeptide 7, cardiac muscle, beta
• ID: MGI:2155600

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0003774	cytoskeletal motor activity	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0000146	microfilament motor activity	ISO	J:164563
Molecular Function	GO:0000146	microfilament motor activity	ISO	J:155856
Molecular Function	GO:0000146	microfilament motor activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:220106
Cellular Component	GO:0005859	muscle myosin complex	ISO	J:155856
Cellular Component	GO:0030016	myofibril	ISO	J:155856
Cellular Component	GO:0030016	myofibril	IDA	J:178379
Cellular Component	GO:0030016	myofibril	IDA	J:51939
Cellular Component	GO:0016459	myosin complex	IDA	J:45687
Cellular Component	GO:0016459	myosin complex	IDA	J:51939
Cellular Component	GO:0032982	myosin filament	ISO	J:164563
Cellular Component	GO:0032982	myosin filament	ISO	J:155856
Cellular Component	GO:0032982	myosin filament	IBA	J:265628
Cellular Component	GO:0016460	myosin II complex	IBA	J:265628
Cellular Component	GO:0030017	sarcomere	ISO	J:155856
Cellular Component	GO:0001725	stress fiber	IDA	J:168709
Cellular Component	GO:0030018	Z disc	IDA	J:168709
Biological Process	GO:0007512	adult heart development	ISO	J:164563
Biological Process	GO:0007512	adult heart development	IBA	J:265628
Biological Process	GO:0046034	ATP metabolic process	ISO	J:164563
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0060048	cardiac muscle contraction	IBA	J:265628
Biological Process	GO:0014898	cardiac muscle hypertrophy in response to stress	IDA	J:211907
Biological Process	GO:0006936	muscle contraction	ISO	J:164563
Biological Process	GO:0006936	muscle contraction	ISO	J:155856
Biological Process	GO:0030049	muscle filament sliding	ISO	J:164563
Biological Process	GO:0030049	muscle filament sliding	IBA	J:265628
Biological Process	GO:0002027	regulation of heart rate	ISO	J:164563
Biological Process	GO:0031449	regulation of slow-twitch skeletal muscle fiber contraction	ISO	J:164563
Biological Process	GO:0002026	regulation of the force of heart contraction	ISO	J:164563
Biological Process	GO:0014728	regulation of the force of skeletal muscle contraction	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	IBA	J:265628
Biological Process	GO:0003009	skeletal muscle contraction	ISO	J:164563
Biological Process	GO:0006941	striated muscle contraction	ISO	J:164563
Biological Process	GO:0014883	transition between fast and slow fiber	IDA	J:143917
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	ISO	J:164563