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GO Annotations Graph
Symbol
Name
ID
Dock2
dedicator of cyto-kinesis 2
MGI:2149010

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005096GTPase activator activityIMPJ:84581
Molecular FunctionGO:0005085guanyl-nucleotide exchange factor activityIEAJ:72247
Molecular FunctionGO:0005085guanyl-nucleotide exchange factor activityIEAJ:60000
Molecular FunctionGO:0030676Rac guanyl-nucleotide exchange factor activityISOJ:164563
Molecular FunctionGO:0042608T cell receptor bindingISOJ:164563
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0016020membraneISOJ:164563
Biological ProcessGO:0030036actin cytoskeleton organizationIEAJ:72247
Biological ProcessGO:0046631alpha-beta T cell activationIMPJ:84581
Biological ProcessGO:0046633alpha-beta T cell proliferationIMPJ:84581
Biological ProcessGO:0006935chemotaxisIMPJ:71005
Biological ProcessGO:0007010cytoskeleton organizationIDAJ:71005
Biological ProcessGO:0001768establishment of T cell polarityIMPJ:84581
Biological ProcessGO:0001771immunological synapse formationIMPJ:84581
Biological ProcessGO:0044351macropinocytosisIMPJ:176441
Biological ProcessGO:0001766membrane raft polarizationIMPJ:84581
Biological ProcessGO:0002277myeloid dendritic cell activation involved in immune responseIMPJ:176441
Biological ProcessGO:0045060negative thymic T cell selectionIMPJ:84581
Biological ProcessGO:0043547positive regulation of GTPase activityISOJ:164563
Biological ProcessGO:0050766positive regulation of phagocytosisIMPJ:176441
Biological ProcessGO:0035022positive regulation of Rac protein signal transductionICJ:84581
Biological ProcessGO:0045059positive thymic T cell selectionIMPJ:84581
Biological ProcessGO:0007264small GTPase mediated signal transductionIEAJ:72247
Biological ProcessGO:0042110T cell activationIMPJ:84581
Biological ProcessGO:0042098T cell proliferationIMPJ:84581


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory