GO Annotations Graph

• Symbol: Kdm5a
• Name: lysine demethylase 5A
• ID: MGI:2136980

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:157630
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:134766
Molecular Function	GO:0051213	dioxygenase activity	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0004857	enzyme inhibitor activity	IDA	J:176119
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0032452	histone demethylase activity	IBA	J:265628
Molecular Function	GO:0032453	histone H3K4 demethylase activity	IMP	J:134766
Molecular Function	GO:0034647	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0035064	methylated histone binding	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:176119
Molecular Function	GO:0005515	protein binding	IPI	J:157630
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:176119
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:134766
Cellular Component	GO:0032993	protein-DNA complex	IDA	J:134766
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:176119
Biological Process	GO:0140718	facultative heterochromatin formation	IDA	J:157630
Biological Process	GO:0016570	histone modification	IMP	J:134766
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:134766
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0048511	rhythmic process	IEA	J:60000