GO Annotations Graph

• Symbol: Cers1
• Name: ceramide synthase 1
• ID: MGI:2136690

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016410	N-acyltransferase activity	IMP	J:172719
Molecular Function	GO:0005515	protein binding	IPI	J:230048
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	ISO	J:164563
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	IDA	J:127737
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	IDA	J:117381
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IDA	J:117381
Biological Process	GO:0007420	brain development	IMP	J:91243
Biological Process	GO:0072721	cellular response to dithiothreitol	ISO	J:164563
Biological Process	GO:0036146	cellular response to mycotoxin	ISO	J:164563
Biological Process	GO:0071492	cellular response to UV-A	ISO	J:164563
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0046513	ceramide biosynthetic process	IDA	J:127737
Biological Process	GO:0046513	ceramide biosynthetic process	IMP	J:172719
Biological Process	GO:0046513	ceramide biosynthetic process	IDA	J:230048
Biological Process	GO:0046513	ceramide biosynthetic process	ISO	J:164563
Biological Process	GO:0046513	ceramide biosynthetic process	IDA	J:117381
Biological Process	GO:0046513	ceramide biosynthetic process	IMP	J:284081
Biological Process	GO:0046513	ceramide biosynthetic process	IBA	J:265628
Biological Process	GO:0046325	negative regulation of glucose import	IMP	J:284081
Biological Process	GO:0051974	negative regulation of telomerase activity	ISO	J:164563
Biological Process	GO:1901526	positive regulation of mitophagy	ISO	J:164563
Biological Process	GO:0030148	sphingolipid biosynthetic process	ISO	J:164563