GO Annotations Graph

• Symbol: Ddrgk1
• Name: DDRGK domain containing 1
• ID: MGI:1924256

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:217277
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:217277
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:73065
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Biological Process	GO:0051216	cartilage development	IMP	J:243374
Biological Process	GO:0051216	cartilage development	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	IMP	J:244198
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	ISO	J:164563
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:1903721	positive regulation of I-kappaB phosphorylation	ISO	J:164563
Biological Process	GO:1905050	positive regulation of metallopeptidase activity	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1901800	positive regulation of proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:1905552	positive regulation of protein localization to endoplasmic reticulum	IDA	J:217277
Biological Process	GO:1905636	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:1990592	protein K69-linked ufmylation	ISO	J:164563
Biological Process	GO:0070972	protein localization to endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0071569	protein ufmylation	ISO	J:164563
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:217277
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:244198
Biological Process	GO:0061709	reticulophagy	ISO	J:164563