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GO Annotations Graph
Symbol
Name
ID
Sost
sclerostin
MGI:1921749

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0008201heparin bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:128100
Molecular FunctionGO:0008134transcription factor bindingISOJ:164563
Cellular ComponentGO:0031012colocalizes_with
extracellular matrix
ISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0005794Golgi apparatusISOJ:155856
Cellular ComponentGO:0043234protein complexISOJ:155856
Cellular ComponentGO:0005578proteinaceous extracellular matrixIEAJ:60000
Biological ProcessGO:0071374cellular response to parathyroid hormone stimulusISOJ:164563
Biological ProcessGO:0030514negative regulation of BMP signaling pathwayISAJ:86838
Biological ProcessGO:0030514negative regulation of BMP signaling pathwayIDAJ:128100
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayIGIJ:154024
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayIGIJ:161416
Biological ProcessGO:0030279negative regulation of ossificationIMPJ:200671
Biological ProcessGO:0031333negative regulation of protein complex assemblyISOJ:164563
Biological ProcessGO:0030178negative regulation of Wnt signaling pathwayIDAJ:128100
Biological ProcessGO:2000054negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specificationISOJ:164563
Biological ProcessGO:0001503ossificationIDAJ:86838
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0016055Wnt signaling pathwayIEAJ:60000


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory