GO Annotations Graph

• Symbol: Thoc1
• Name: THO complex 1
• ID: MGI:1919668

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:204143
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0000347	THO complex	ISO	J:164563
Cellular Component	GO:0000445	THO complex part of transcription export complex	ISO	J:164563
Cellular Component	GO:0000445	THO complex part of transcription export complex	IBA	J:265628
Cellular Component	GO:0000346	transcription export complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	RCA	J:84168
Biological Process	GO:0006406	mRNA export from nucleus	ISO	J:164563
Biological Process	GO:0006406	mRNA export from nucleus	IBA	J:265628
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0051028	mRNA transport	IEA	J:60000
Biological Process	GO:2000002	negative regulation of DNA damage checkpoint	ISO	J:164563
Biological Process	GO:0048297	negative regulation of isotype switching to IgA isotypes	IMP	J:202582
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	RCA	J:84168
Biological Process	GO:0000018	regulation of DNA recombination	ISO	J:164563
Biological Process	GO:0032784	regulation of DNA-templated transcription elongation	ISO	J:164563
Biological Process	GO:0032784	regulation of DNA-templated transcription elongation	IBA	J:265628
Biological Process	GO:0031297	replication fork processing	ISO	J:164563
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0046784	viral mRNA export from host cell nucleus	ISO	J:164563