GO Annotations Graph

• Symbol: Sash1
• Name: SAM and SH3 domain containing 1
• ID: MGI:1917347

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:164563
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	IBA	J:265628
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:205449
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:205449
Molecular Function	GO:0005515	protein binding	ISO	J:205449
Molecular Function	GO:0019901	protein kinase binding	ISO	J:205449
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:205449
Cellular Component	GO:0032991	protein-containing complex	ISO	J:205449
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:205449
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ISO	J:205449
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IBA	J:265628
Biological Process	GO:0043507	positive regulation of JUN kinase activity	ISO	J:205449
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	ISO	J:205449
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:205449
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	ISO	J:205449
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:205449
Biological Process	GO:0010632	regulation of epithelial cell migration	ISO	J:164563
Biological Process	GO:1902498	regulation of protein autoubiquitination	ISO	J:205449
Biological Process	GO:1900044	regulation of protein K63-linked ubiquitination	ISO	J:205449