About   Help   FAQ
GO Annotations Graph
Symbol
Name
ID
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
MGI:1917258

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0004180carboxypeptidase activityISOJ:164563
Molecular FunctionGO:0004180carboxypeptidase activityTASJ:77232
Molecular FunctionGO:0004180carboxypeptidase activityISOJ:155856
Molecular FunctionGO:0004175endopeptidase activityISOJ:164563
Molecular FunctionGO:0001948glycoprotein bindingISOJ:164563
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0008237metallopeptidase activityIEAJ:72247
Molecular FunctionGO:0008237metallopeptidase activityIEAJ:60000
Molecular FunctionGO:0008233peptidase activityIEAJ:60000
Molecular FunctionGO:0008241peptidyl-dipeptidase activityIEAJ:72247
Molecular FunctionGO:0001618virus receptor activityISOJ:164563
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:213091
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionISOJ:164563
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneIDAJ:213091
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0003051angiotensin-mediated drinking behaviorISOJ:164563
Biological ProcessGO:0070373negative regulation of ERK1 and ERK2 cascadeISOJ:155856
Biological ProcessGO:0048662negative regulation of smooth muscle cell proliferationISOJ:155856
Biological ProcessGO:0060452positive regulation of cardiac muscle contractionIMPJ:77232
Biological ProcessGO:1903598positive regulation of gap junction assemblyISOJ:164563
Biological ProcessGO:0006508proteolysisIEAJ:60000
Biological ProcessGO:0006508proteolysisIEAJ:72247
Biological ProcessGO:0032800receptor biosynthetic processISOJ:164563
Biological ProcessGO:0046813receptor-mediated virion attachment to host cellISOJ:164563
Biological ProcessGO:1903779regulation of cardiac conductionISOJ:164563
Biological ProcessGO:0003081regulation of systemic arterial blood pressure by renin-angiotensinISOJ:164563
Biological ProcessGO:0015827tryptophan transportIMPJ:186775


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/31/2020
MGI 6.15
The Jackson Laboratory