GO Annotations Graph

• Symbol: Wls
• Name: wntless WNT ligand secretion mediator
• ID: MGI:1915401

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0031852	mu-type opioid receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:154679
Molecular Function	GO:0005515	protein binding	IPI	J:154679
Molecular Function	GO:0005515	protein binding	IPI	J:299450
Molecular Function	GO:0005515	protein binding	IPI	J:299450
Molecular Function	GO:0005515	protein binding	IPI	J:299450
Molecular Function	GO:0017147	Wnt-protein binding	ISO	J:164563
Molecular Function	GO:0017147	Wnt-protein binding	IDA	J:154679
Molecular Function	GO:0017147	Wnt-protein binding	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:154679
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0032839	dendrite cytoplasm	ISO	J:155856
Cellular Component	GO:0032590	dendrite membrane	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0012505	endomembrane system	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:299450
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:154679
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:299450
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Biological Process	GO:0009948	anterior/posterior axis specification	IMP	J:154679
Biological Process	GO:0071529	cementum mineralization	IGI	J:279653
Biological Process	GO:0071529	cementum mineralization	IGI	J:279653
Biological Process	GO:0031017	exocrine pancreas development	IMP	J:164701
Biological Process	GO:0030902	hindbrain development	IMP	J:164701
Biological Process	GO:0006886	intracellular protein transport	ISO	J:164563
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:0001707	mesoderm formation	IMP	J:154679
Biological Process	GO:0030901	midbrain development	IMP	J:164701
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:164701
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0061357	positive regulation of Wnt protein secretion	ISO	J:164563
Biological Process	GO:0061357	positive regulation of Wnt protein secretion	ISS	J:225410
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ISS	J:225410
Biological Process	GO:0061355	Wnt protein secretion	ISO	J:164563
Biological Process	GO:0061355	Wnt protein secretion	IBA	J:265628
Biological Process	GO:0061355	Wnt protein secretion	IDA	J:299450
Biological Process	GO:0016055	Wnt signaling pathway	IMP	J:154679