GO Annotations Graph

• Symbol: Dgat2
• Name: diacylglycerol O-acyltransferase 2
• ID: MGI:1915050

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003846	2-acylglycerol O-acyltransferase activity	IDA	J:77354
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	ISO	J:155856
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	ISO	J:164563
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	IBA	J:265628
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	IMP	J:176988
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	IDA	J:72182
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	IDA	J:217946
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	IDA	J:77354
Molecular Function	GO:0008374	O-acyltransferase activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:176988
Molecular Function	GO:0050252	retinol O-fatty-acyltransferase activity	IEA	J:72245
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:147912
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:217946
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:176988
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:176988
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0005811	lipid droplet	IDA	J:147912
Cellular Component	GO:0005811	lipid droplet	ISO	J:164563
Cellular Component	GO:0005811	lipid droplet	IDA	J:176988
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:77354
Cellular Component	GO:0016020	membrane	IDA	J:72182
Cellular Component	GO:0005739	mitochondrion	IDA	J:147912
Cellular Component	GO:1990578	perinuclear endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:147912
Biological Process	GO:0071400	cellular response to oleic acid	IMP	J:176988
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:133527
Biological Process	GO:0006651	diacylglycerol biosynthetic process	IDA	J:192630
Biological Process	GO:0046339	diacylglycerol metabolic process	ISO	J:164563
Biological Process	GO:0046339	diacylglycerol metabolic process	ISO	J:155856
Biological Process	GO:0046339	diacylglycerol metabolic process	IDA	J:72182
Biological Process	GO:0046339	diacylglycerol metabolic process	IBA	J:265628
Biological Process	GO:0060613	fat pad development	IMP	J:133527
Biological Process	GO:0055089	fatty acid homeostasis	IGI	J:133527
Biological Process	GO:0006071	glycerol metabolic process	IEA	J:60000
Biological Process	GO:0035356	intracellular triglyceride homeostasis	IMP	J:88742
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0019915	lipid storage	IGI	J:180646
Biological Process	GO:0019915	lipid storage	IMP	J:176988
Biological Process	GO:0035336	long-chain fatty-acyl-CoA metabolic process	ISO	J:164563
Biological Process	GO:0035336	long-chain fatty-acyl-CoA metabolic process	IDA	J:72182
Biological Process	GO:0034383	low-density lipoprotein particle clearance	IMP	J:133757
Biological Process	GO:0006640	monoacylglycerol biosynthetic process	ISO	J:164563
Biological Process	GO:0046322	negative regulation of fatty acid oxidation	ISO	J:155856
Biological Process	GO:0045722	positive regulation of gluconeogenesis	ISO	J:155856
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	ISO	J:155856
Biological Process	GO:0090181	regulation of cholesterol metabolic process	ISO	J:155856
Biological Process	GO:0050746	regulation of lipoprotein metabolic process	ISO	J:155856
Biological Process	GO:0097006	regulation of plasma lipoprotein particle levels	IMP	J:133527
Biological Process	GO:0019432	triglyceride biosynthetic process	ISO	J:164563
Biological Process	GO:0019432	triglyceride biosynthetic process	IBA	J:265628
Biological Process	GO:0019432	triglyceride biosynthetic process	IMP	J:176988
Biological Process	GO:0019432	triglyceride biosynthetic process	IMP	J:88742
Biological Process	GO:0019432	triglyceride biosynthetic process	IDA	J:72182
Biological Process	GO:0019432	triglyceride biosynthetic process	IDA	J:77354