Slc39a8 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Slc39a8
solute carrier family 39 (metal ion transporter), member 8
MGI:1914797

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046873	metal ion transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	IDA	J:282723
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	IDA	J:282682
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	ISO	J:164563
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	IDA	J:282595
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	IDA	J:244002
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	IDA	J:282682
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	IBA	J:265628
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0140412	zinc:bicarbonate symporter activity	IDA	J:282595
Molecular Function	GO:0140412	zinc:bicarbonate symporter activity	IDA	J:258360
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:244002
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:125886
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:282682
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031090	organelle membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:282595
Cellular Component	GO:0005886	plasma membrane	IDA	J:282723
Cellular Component	GO:0005886	plasma membrane	IDA	J:96980
Biological Process	GO:0006525	arginine metabolic process	IMP	J:244002
Biological Process	GO:0015701	bicarbonate transport	IDA	J:282682
Biological Process	GO:0015701	bicarbonate transport	IDA	J:282595
Biological Process	GO:0070574	cadmium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0070574	cadmium ion transmembrane transport	IDA	J:282595
Biological Process	GO:0070574	cadmium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0070574	cadmium ion transmembrane transport	IMP	J:282611
Biological Process	GO:0070574	cadmium ion transmembrane transport	IDA	J:282682
Biological Process	GO:0070574	cadmium ion transmembrane transport	IDA	J:96980
Biological Process	GO:1990079	cartilage homeostasis	IMP	J:212038
Biological Process	GO:0098849	cellular detoxification of cadmium ion	ISO	J:164563
Biological Process	GO:0006824	cobalt ion transport	ISO	J:155856
Biological Process	GO:0006351	DNA-templated transcription	IMP	J:212038
Biological Process	GO:0030198	extracellular matrix organization	ISO	J:164563
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:258360
Biological Process	GO:0030026	intracellular manganese ion homeostasis	IMP	J:244002
Biological Process	GO:0030003	intracellular monoatomic cation homeostasis	IBA	J:265628
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IDA	J:212038
Biological Process	GO:0006882	intracellular zinc ion homeostasis	ISO	J:164563
Biological Process	GO:0098711	iron ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0098711	iron ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0098711	iron ion import across plasma membrane	IDA	J:328866
Biological Process	GO:0098711	iron ion import across plasma membrane	IMP	J:282611
Biological Process	GO:0061757	leukocyte adhesion to arterial endothelial cell	IMP	J:282611
Biological Process	GO:0071421	manganese ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071421	manganese ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071421	manganese ion transmembrane transport	IMP	J:244002
Biological Process	GO:0071421	manganese ion transmembrane transport	IDA	J:282682
Biological Process	GO:0015694	mercury ion transport	IDA	J:282682
Biological Process	GO:0030001	metal ion transport	IEA	J:72247
Biological Process	GO:1990540	mitochondrial manganese ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0097080	plasma membrane selenite transport	IDA	J:282723
Biological Process	GO:0097080	plasma membrane selenite transport	ISO	J:164563
Biological Process	GO:0006487	protein N-linked glycosylation	IMP	J:244002
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:258360
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0071578	zinc ion import across plasma membrane	IMP	J:282611
Biological Process	GO:0071578	zinc ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0071578	zinc ion import across plasma membrane	IDA	J:282595
Biological Process	GO:0071578	zinc ion import across plasma membrane	IMP	J:258360
Biological Process	GO:0071578	zinc ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0071577	zinc ion transmembrane transport	IMP	J:212038
Biological Process	GO:0071577	zinc ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006829	zinc ion transport	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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