GO Annotations Graph

• Symbol: Dlg3
• Name: discs large MAGUK scaffold protein 3
• ID: MGI:1888986

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0019900	kinase binding	ISO	J:168713
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0019902	phosphatase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:263407
Molecular Function	GO:0005515	protein binding	IPI	J:145953
Molecular Function	GO:0005515	protein binding	IPI	J:152628
Molecular Function	GO:0005515	protein binding	IPI	J:225474
Molecular Function	GO:0005515	protein binding	IPI	J:249721
Molecular Function	GO:0005515	protein binding	IPI	J:113926
Molecular Function	GO:0005515	protein binding	IPI	J:215971
Molecular Function	GO:0005515	protein binding	IPI	J:80555
Molecular Function	GO:0005515	protein binding	IPI	J:113153
Molecular Function	GO:0005515	protein binding	IPI	J:113153
Molecular Function	GO:0005515	protein binding	IPI	J:113153
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:155856
Molecular Function	GO:0098919	structural constituent of postsynaptic density	ISO	J:155856
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:178643
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:178643
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IDA	J:188364
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:178643
Cellular Component	GO:0005911	cell-cell junction	IDA	J:178643
Cellular Component	GO:0005911	cell-cell junction	IDA	J:178643
Cellular Component	GO:0005737	cytoplasm	IDA	J:178643
Cellular Component	GO:0005737	cytoplasm	IDA	J:80555
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:218184
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:122983
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:122983
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:122983
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:122983
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:122983
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:122983
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0031594	neuromuscular junction	IBA	J:265628
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-443767
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9668214
Cellular Component	GO:0005886	plasma membrane	IDA	J:178643
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0099092	postsynaptic density, intracellular component	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0001736	establishment of planar polarity	IMP	J:178643
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IMP	J:178643
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	ISO	J:155856
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IMP	J:122983
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:122983
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:122983
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:122983
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IMP	J:122983
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:122983