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GO Annotations Graph
Symbol
Name
ID
Lats2
large tumor suppressor 2
MGI:1354386

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0004674protein serine/threonine kinase activityIBAJ:161428
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0005815microtubule organizing centerISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:73065
Cellular ComponentGO:0005634nucleusIBAJ:161428
Cellular ComponentGO:0000922spindle poleIDAJ:93191
Cellular ComponentGO:0000922spindle poleISOJ:164563
Biological ProcessGO:0007049cell cycleIEAJ:60000
Biological ProcessGO:0051301cell divisionIEAJ:60000
Biological ProcessGO:0034613cellular protein localizationIDAJ:147050
Biological ProcessGO:0034613cellular protein localizationIGIJ:147050
Biological ProcessGO:0000082G1/S transition of mitotic cell cycleISOJ:164563
Biological ProcessGO:0000082G1/S transition of mitotic cell cycleIDAJ:93191
Biological ProcessGO:0035329hippo signalingIGIJ:134270
Biological ProcessGO:0035329hippo signalingISOJ:164563
Biological ProcessGO:0009755hormone-mediated signaling pathwayISOJ:164563
Biological ProcessGO:0001827inner cell mass cell fate commitmentIGIJ:199456
Biological ProcessGO:0001828inner cell mass cellular morphogenesisIGIJ:199456
Biological ProcessGO:0035556intracellular signal transductionISOJ:164563
Biological ProcessGO:0030216keratinocyte differentiationIGIJ:134270
Biological ProcessGO:0007067mitotic nuclear divisionIEAJ:72247
Biological ProcessGO:0007067mitotic nuclear divisionIEAJ:60000
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayIGIJ:170963
Biological ProcessGO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activityISOJ:164563
Biological ProcessGO:0018105peptidyl-serine phosphorylationIBAJ:161428
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0043065positive regulation of apoptotic processIBAJ:161428
Biological ProcessGO:0006468protein phosphorylationIDAJ:147050
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0046620regulation of organ growthIMPJ:170963


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory