GO Annotations Graph

• Symbol: Trpm2
• Name: transient receptor potential cation channel, subfamily M, member 2
• ID: MGI:1351901

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Wed Mar 2 12:11:24 2016.

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047631	ADP-ribose diphosphatase activity	IEA	J:72245
Molecular Function	GO:0047631	ADP-ribose diphosphatase activity	IEA	J:72247
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005261	cation channel activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0005216	ion channel activity	IEA	J:72247
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	IDA	J:137259
Molecular Function	GO:0005272	sodium channel activity	IEA	J:60000
Cellular Component	GO:0016021	integral component of membrane	IEA	J:72247
Cellular Component	GO:0016021	integral component of membrane	IEA	J:60000
Cellular Component	GO:0005622	intracellular	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:137259
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0098703	calcium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0006812	cation transport	IEA	J:72247
Biological Process	GO:0034220	ion transmembrane transport	IEA	J:72247
Biological Process	GO:0006811	ion transport	IEA	J:72247
Biological Process	GO:0006811	ion transport	IEA	J:60000
Biological Process	GO:0006828	manganese ion transport	IDA	J:137259
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:1903223	positive regulation of oxidative stress-induced neuron death	ISO	J:155856
Biological Process	GO:0033194	response to hydroperoxide	IDA	J:137259
Biological Process	GO:0006979	response to oxidative stress	IEA	J:72247
Biological Process	GO:0006814	sodium ion transport	IEA	J:60000
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0006810	transport	IEA	J:60000

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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