Grm4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Grm4
glutamate receptor, metabotropic 4
MGI:1351341

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001640	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	IBA	J:265628
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	ISO	J:155856
Molecular Function	GO:0004930	G protein-coupled receptor activity	ISO	J:164563
Molecular Function	GO:0008066	glutamate receptor activity	ISO	J:164563
Molecular Function	GO:0001642	group III metabotropic glutamate receptor activity	TAS	J:35793
Cellular Component	GO:0150048	cerebellar granule cell to Purkinje cell synapse	IDA	J:326657
Cellular Component	GO:0150048	cerebellar granule cell to Purkinje cell synapse	IDA	J:326657
Cellular Component	GO:0150048	cerebellar granule cell to Purkinje cell synapse	IDA	J:326657
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263466
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263466
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263466
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263466
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263466
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263466
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:35793
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:35793
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:35793
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:35793
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326657
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326657
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326657
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043005	neuron projection	IDA	J:184110
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IDA	J:35793
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	EXP	J:35793
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IDA	J:35793
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IMP	J:35793
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:263466
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:263466
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:263466
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:263466
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:263466
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:263466
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:326657
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:326657
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:326657
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:326657
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:326657
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:326657
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0007196	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:35793
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007612	learning	IMP	J:35793
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:35793
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:35793
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:35793
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:35793
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:35793
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:35793
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:35793
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:35793
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:60000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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