GO Annotations Graph

• Symbol: Atp1a4
• Name: ATPase, Na+/K+ transporting, alpha 4 polypeptide
• ID: MGI:1351335

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Wed Mar 2 12:11:24 2016.

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	IDA	J:203477
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	IMP	J:169420
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	ISO	J:73065
Cellular Component	GO:0016021	integral component of membrane	IEA	J:60000
Cellular Component	GO:0016021	integral component of membrane	IEA	J:72247
Cellular Component	GO:0005887	integral component of plasma membrane	IBA	J:161428
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:161428
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0015991	ATP hydrolysis coupled proton transport	IBA	J:161428
Biological Process	GO:0030007	cellular potassium ion homeostasis	IBA	J:161428
Biological Process	GO:0006883	cellular sodium ion homeostasis	IBA	J:161428
Biological Process	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	ISO	J:155856
Biological Process	GO:0009566	fertilization	IMP	J:169420
Biological Process	GO:0006811	ion transport	IEA	J:60000
Biological Process	GO:0010107	potassium ion import	IBA	J:161428
Biological Process	GO:0006813	potassium ion transport	IEA	J:72247
Biological Process	GO:0006813	potassium ion transport	IEA	J:60000
Biological Process	GO:0030641	regulation of cellular pH	ISO	J:155856
Biological Process	GO:0030641	regulation of cellular pH	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:169420
Biological Process	GO:0036376	sodium ion export from cell	IBA	J:161428
Biological Process	GO:0006814	sodium ion transport	IMP	J:169420
Biological Process	GO:0030317	sperm motility	IMP	J:169420
Biological Process	GO:0030317	sperm motility	ISO	J:164563
Biological Process	GO:0030317	sperm motility	ISO	J:155856
Biological Process	GO:0007283	spermatogenesis	IMP	J:169420
Biological Process	GO:0006810	transport	IEA	J:60000

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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