GO Annotations Graph

• Symbol: Slc7a11
• Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
• ID: MGI:1347355

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015327	cystine:glutamate antiporter activity	ISO	J:164563
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0140926	L-kynurenine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0045177	apical part of cell	IDA	J:108457
Cellular Component	GO:0097449	astrocyte projection	IDA	J:108457
Cellular Component	GO:0031526	brush border membrane	IDA	J:108457
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:258726
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:108457
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0030534	adult behavior	IDA	J:256101
Biological Process	GO:0003333	amino acid transmembrane transport	IBA	J:265628
Biological Process	GO:0006865	amino acid transport	IEA	J:72247
Biological Process	GO:0006865	amino acid transport	IEA	J:60000
Biological Process	GO:0007420	brain development	IMP	J:113249
Biological Process	GO:0034599	cellular response to oxidative stress	IMP	J:113249
Biological Process	GO:0034599	cellular response to oxidative stress	IMP	J:193772
Biological Process	GO:0034599	cellular response to oxidative stress	IDA	J:113249
Biological Process	GO:0033554	cellular response to stress	IDA	J:256101
Biological Process	GO:0140206	dipeptide import across plasma membrane	IMP	J:100476
Biological Process	GO:0006749	glutathione metabolic process	IMP	J:121453
Biological Process	GO:0006749	glutathione metabolic process	IMP	J:193772
Biological Process	GO:0034775	glutathione transmembrane transport	IDA	J:113249
Biological Process	GO:0090461	intracellular glutamate homeostasis	IGI	J:256101
Biological Process	GO:0090461	intracellular glutamate homeostasis	IMP	J:170726
Biological Process	GO:0015811	L-cystine transport	IMP	J:100476
Biological Process	GO:0015811	L-cystine transport	ISO	J:164563
Biological Process	GO:0098712	L-glutamate import across plasma membrane	IMP	J:170967
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:164563
Biological Process	GO:0140924	L-kynurenine transmembrane transport	ISO	J:164563
Biological Process	GO:0060173	limb development	IMP	J:170967
Biological Process	GO:0048286	lung alveolus development	IMP	J:193772
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:218184
Biological Process	GO:0110076	negative regulation of ferroptosis	ISO	J:164563
Biological Process	GO:0071702	organic substance transport	IMP	J:102902
Biological Process	GO:0071702	organic substance transport	IMP	J:100476
Biological Process	GO:0071702	organic substance transport	IMP	J:121453
Biological Process	GO:0070527	platelet aggregation	IMP	J:31616
Biological Process	GO:1904717	regulation of AMPA glutamate receptor clustering	IMP	J:218184
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:128443
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:100476
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:113249
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	IMP	J:100476
Biological Process	GO:1901494	regulation of cysteine metabolic process	IMP	J:121453
Biological Process	GO:2000211	regulation of glutamate metabolic process	IMP	J:170967
Biological Process	GO:2000211	regulation of glutamate metabolic process	IMP	J:218184
Biological Process	GO:2000211	regulation of glutamate metabolic process	IMP	J:208250
Biological Process	GO:1903786	regulation of glutathione biosynthetic process	IMP	J:100476
Biological Process	GO:0048021	regulation of melanin biosynthetic process	IMP	J:100476
Biological Process	GO:0033029	regulation of neutrophil apoptotic process	IMP	J:121453
Biological Process	GO:0051223	regulation of protein transport	IMP	J:100476
Biological Process	GO:0050807	regulation of synapse organization	IMP	J:218184
Biological Process	GO:0014070	response to organic cyclic compound	IMP	J:170726
Biological Process	GO:0051775	response to redox state	IMP	J:102902
Biological Process	GO:0009636	response to toxic substance	ISO	J:164563
Biological Process	GO:0021756	striatum development	IMP	J:113249
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0021591	ventricular system development	IMP	J:113249
Biological Process	GO:0008542	visual learning	IMP	J:208250
Biological Process	GO:0008542	visual learning	IMP	J:170967