GO Annotations Graph

• Symbol: Gla
• Name: galactosidase, alpha
• ID: MGI:1347344

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004557	alpha-galactosidase activity	ISO	J:155856
Molecular Function	GO:0004557	alpha-galactosidase activity	ISO	J:164563
Molecular Function	GO:0004557	alpha-galactosidase activity	IBA	J:265628
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:8903
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:6384
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:5755
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:7062
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:5872
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:5868
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:5963
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:62906
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:9627
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:66863
Molecular Function	GO:0004557	alpha-galactosidase activity	IMP	J:39394
Molecular Function	GO:0004557	alpha-galactosidase activity	IDA	J:95445
Molecular Function	GO:0003824	catalytic activity	ISO	J:164563
Molecular Function	GO:0016936	galactoside binding	ISO	J:155856
Molecular Function	GO:0017041	galactosylgalactosylglucosylceramidase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IDA	J:164482
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEA	J:60000
Molecular Function	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0052692	raffinose alpha-galactosidase activity	IEA	J:72245
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:164482
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IDA	J:95445
Biological Process	GO:0035904	aorta development	IMP	J:289408
Biological Process	GO:0005975	carbohydrate metabolic process	IEA	J:72247
Biological Process	GO:0016139	glycoside catabolic process	IBA	J:265628
Biological Process	GO:0046479	glycosphingolipid catabolic process	ISO	J:164563
Biological Process	GO:0046477	glycosylceramide catabolic process	IMP	J:62764
Biological Process	GO:0046477	glycosylceramide catabolic process	IMP	J:39394
Biological Process	GO:0046477	glycosylceramide catabolic process	IMP	J:73481
Biological Process	GO:0046477	glycosylceramide catabolic process	IDA	J:62906
Biological Process	GO:0046477	glycosylceramide catabolic process	IDA	J:95445
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	IMP	J:108541
Biological Process	GO:0051001	negative regulation of nitric-oxide synthase activity	IMP	J:108541
Biological Process	GO:0009311	oligosaccharide metabolic process	ISO	J:164563
Biological Process	GO:0009311	oligosaccharide metabolic process	IBA	J:265628