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GO Annotations Graph
Symbol
Name
ID
Map3k7
mitogen-activated protein kinase kinase kinase 7
MGI:1346877

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0004708MAP kinase kinase activityIDAJ:80766
Molecular FunctionGO:0004709MAP kinase kinase kinase activityIBAJ:161428
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:208236
Molecular FunctionGO:0005515protein bindingIPIJ:84524
Molecular FunctionGO:0005515protein bindingIPIJ:84524
Molecular FunctionGO:0005515protein bindingIPIJ:206842
Molecular FunctionGO:0005515protein bindingIPIJ:201312
Molecular FunctionGO:0005515protein bindingIPIJ:120934
Molecular FunctionGO:0005515protein bindingIPIJ:179005
Molecular FunctionGO:0005515protein bindingIPIJ:148055
Molecular FunctionGO:0005515protein bindingIPIJ:166091
Molecular FunctionGO:0005515protein bindingIPIJ:150837
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004674protein serine/threonine kinase activityIEAJ:60000
Molecular FunctionGO:0097110scaffold protein bindingISOJ:205449
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005622intracellularIBAJ:161428
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0097481neuronal postsynaptic densityIDAJ:187362
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0000186activation of MAPKK activityIBAJ:161428
Biological ProcessGO:0001525angiogenesisIMPJ:107401
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0007252I-kappaB phosphorylationIGIJ:102721
Biological ProcessGO:0000165MAPK cascadeIDAJ:84524
Biological ProcessGO:2001234negative regulation of apoptotic signaling pathwayIGIJ:102721
Biological ProcessGO:2001234negative regulation of apoptotic signaling pathwayIMPJ:102721
Biological ProcessGO:0060546negative regulation of necroptotic processIMPJ:182381
Biological ProcessGO:2000378negative regulation of reactive oxygen species metabolic processIMPJ:182381
Biological ProcessGO:1902443negative regulation of ripoptosome assembly involved in necroptotic processIGIJ:182381
Biological ProcessGO:0001841neural tube formationIMPJ:102721
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0043123positive regulation of I-kappaB kinase/NF-kappaB signalingIGIJ:102721
Biological ProcessGO:0046330positive regulation of JNK cascadeIGIJ:102721
Biological ProcessGO:0006468protein phosphorylationIDAJ:80766
Biological ProcessGO:2000377regulation of reactive oxygen species metabolic processIMPJ:182381
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayIMPJ:102271


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory