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GO Annotations Graph
Symbol
Name
ID
Tlr6
toll-like receptor 6
MGI:1341296

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0042498diacyl lipopeptide bindingIDAJ:156189
Molecular FunctionGO:0071723lipopeptide bindingISOJ:155856
Molecular FunctionGO:0071723lipopeptide bindingIMPJ:70578
Molecular FunctionGO:0046982protein heterodimerization activityIPIJ:156189
Molecular FunctionGO:0035663Toll-like receptor 2 bindingISOJ:164563
Molecular FunctionGO:0004888transmembrane signaling receptor activityIEAJ:72247
Cellular ComponentGO:0031410cytoplasmic vesicleIEAJ:60000
Cellular ComponentGO:0005794Golgi apparatusISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0045121membrane raftISOJ:164563
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0035355Toll-like receptor 2-Toll-like receptor 6 protein complexIDAJ:156189
Biological ProcessGO:0071726cellular response to diacyl bacterial lipopeptideISOJ:73065
Biological ProcessGO:0042496detection of diacyl bacterial lipopeptideISOJ:73065
Biological ProcessGO:0006955immune responseIEAJ:72247
Biological ProcessGO:0002376immune system processIEAJ:60000
Biological ProcessGO:0006954inflammatory responseISOJ:155856
Biological ProcessGO:0045087innate immune responseIEAJ:60000
Biological ProcessGO:0050702interleukin-1 beta secretionIDAJ:205721
Biological ProcessGO:0001774microglial cell activationISOJ:155856
Biological ProcessGO:0002755MyD88-dependent toll-like receptor signaling pathwayIEAJ:72247
Biological ProcessGO:0046209nitric oxide metabolic processISOJ:155856
Biological ProcessGO:0043123positive regulation of I-kappaB kinase/NF-kappaB signalingISOJ:73065
Biological ProcessGO:0045084positive regulation of interleukin-12 biosynthetic processNASJ:135494
Biological ProcessGO:0045410positive regulation of interleukin-6 biosynthetic processISSJ:103395
Biological ProcessGO:0043507positive regulation of JUN kinase activityISOJ:73065
Biological ProcessGO:1900227positive regulation of NLRP3 inflammasome complex assemblyIDAJ:205721
Biological ProcessGO:0050707regulation of cytokine secretionIEAJ:72247
Biological ProcessGO:0032493response to bacterial lipoproteinISOJ:155856
Biological ProcessGO:0007165signal transductionIEAJ:72247
Biological ProcessGO:0042088T-helper 1 type immune responseICJ:135494
Biological ProcessGO:0034150toll-like receptor 6 signaling pathwayIEAJ:72247
Biological ProcessGO:0002224toll-like receptor signaling pathwayISOJ:155856


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/02/2021
MGI 6.16
The Jackson Laboratory