GO Annotations Graph

• Symbol: Fkbp8
• Name: FK506 binding protein 8
• ID: MGI:1341070

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016853	isomerase activity	IEA	J:60000
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEA	J:72245
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEA	J:60000
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:272245
Molecular Function	GO:0005515	protein binding	IPI	J:272245
Molecular Function	GO:0044183	protein folding chaperone	IBA	J:265628
Molecular Function	GO:0044183	protein folding chaperone	IMP	J:272245
Molecular Function	GO:0044183	protein folding chaperone	ISO	J:272245
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0012505	endomembrane system	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:89364
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005740	mitochondrial envelope	IBA	J:265628
Cellular Component	GO:0005740	mitochondrial envelope	IDA	J:89364
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IMP	J:132031
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:138713
Biological Process	GO:0043010	camera-type eye development	IMP	J:89364
Biological Process	GO:0001708	cell fate specification	IMP	J:138713
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IGI	J:138713
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IMP	J:138713
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IGI	J:138713
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IMP	J:132031
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IDA	J:138713
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:89364
Biological Process	GO:0035264	multicellular organism growth	IGI	J:138713
Biological Process	GO:0043066	negative regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:132031
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0021915	neural tube development	IMP	J:138713
Biological Process	GO:0048665	neuron fate specification	IMP	J:89364
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IMP	J:138713
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0006457	protein folding	ISO	J:272245
Biological Process	GO:0006457	protein folding	IMP	J:272245
Biological Process	GO:0070585	protein localization to mitochondrion	ISO	J:164563
Biological Process	GO:1903146	regulation of autophagy of mitochondrion	ISO	J:164563
Biological Process	GO:0030510	regulation of BMP signaling pathway	IGI	J:138713
Biological Process	GO:0010468	regulation of gene expression	IGI	J:138713
Biological Process	GO:0007224	smoothened signaling pathway	IMP	J:89364
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:89364