Bmpr1a GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Bmpr1a
bone morphogenetic protein receptor, type 1A
MGI:1338938

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0036122	BMP binding	IDA	J:299317
Molecular Function	GO:0036122	BMP binding	IDA	J:299322
Molecular Function	GO:0098821	BMP receptor activity	IMP	J:229306
Molecular Function	GO:0098821	BMP receptor activity	IMP	J:299435
Molecular Function	GO:0098821	BMP receptor activity	IDA	J:299322
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:228024
Molecular Function	GO:0005515	protein binding	IPI	J:93750
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAS	J:299435
Molecular Function	GO:0046332	SMAD binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0005025	transforming growth factor beta receptor activity, type I	IBA	J:265628
Molecular Function	GO:0004675	transmembrane receptor protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0004675	transmembrane receptor protein serine/threonine kinase activity	IEA	J:72247
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:268021
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:92179
Biological Process	GO:0060928	atrioventricular node cell development	IMP	J:142986
Biological Process	GO:0003171	atrioventricular valve development	IMP	J:75084
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:229306
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:164563
Biological Process	GO:0030509	BMP signaling pathway	IBA	J:265628
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:299435
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:101432
Biological Process	GO:0030509	BMP signaling pathway	IDA	J:42602
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:124681
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:119568
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:101432
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:109016
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:109016
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:124681
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:101432
Biological Process	GO:0061312	BMP signaling pathway involved in heart development	IMP	J:75084
Biological Process	GO:0061312	BMP signaling pathway involved in heart development	IC	J:89521
Biological Process	GO:0003161	cardiac conduction system development	IMP	J:111392
Biological Process	GO:0003215	cardiac right ventricle morphogenesis	IMP	J:89521
Biological Process	GO:0051216	cartilage development	IMP	J:97780
Biological Process	GO:0071773	cellular response to BMP stimulus	ISO	J:164563
Biological Process	GO:0071363	cellular response to growth factor stimulus	IBA	J:265628
Biological Process	GO:0021953	central nervous system neuron differentiation	IGI	J:93603
Biological Process	GO:0002062	chondrocyte differentiation	IDA	J:202818
Biological Process	GO:0048589	developmental growth	IMP	J:121318
Biological Process	GO:0048589	developmental growth	IMP	J:121318
Biological Process	GO:0035912	dorsal aorta morphogenesis	IMP	J:139945
Biological Process	GO:0009950	dorsal/ventral axis specification	IMP	J:84878
Biological Process	GO:0009953	dorsal/ventral pattern formation	IBA	J:265628
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:96964
Biological Process	GO:0007398	ectoderm development	IMP	J:92178
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:157085
Biological Process	GO:0048598	embryonic morphogenesis	IMP	J:97214
Biological Process	GO:0048568	embryonic organ development	IMP	J:75084
Biological Process	GO:0048568	embryonic organ development	IMP	J:121318
Biological Process	GO:0048568	embryonic organ development	IMP	J:121318
Biological Process	GO:0003272	endocardial cushion formation	IMP	J:104417
Biological Process	GO:0003203	endocardial cushion morphogenesis	IMP	J:75084
Biological Process	GO:0003203	endocardial cushion morphogenesis	IMP	J:89521
Biological Process	GO:0007492	endoderm development	IMP	J:92179
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:106392
Biological Process	GO:1905285	fibrous ring of heart morphogenesis	IMP	J:111392
Biological Process	GO:0007507	heart development	IMP	J:107396
Biological Process	GO:0007507	heart development	IMP	J:107396
Biological Process	GO:0060914	heart formation	IMP	J:119568
Biological Process	GO:0003007	heart morphogenesis	IMP	J:121318
Biological Process	GO:0003007	heart morphogenesis	IMP	J:121318
Biological Process	GO:0035137	hindlimb morphogenesis	IMP	J:107396
Biological Process	GO:0006955	immune response	ISO	J:164563
Biological Process	GO:0001701	in utero embryonic development	IMP	J:121318
Biological Process	GO:0001701	in utero embryonic development	IMP	J:121318
Biological Process	GO:0048368	lateral mesoderm development	IMP	J:119568
Biological Process	GO:0030324	lung development	IMP	J:106392
Biological Process	GO:0048382	mesendoderm development	IMP	J:92179
Biological Process	GO:0001707	mesoderm formation	IMP	J:124681
Biological Process	GO:0003183	mitral valve morphogenesis	IMP	J:111392
Biological Process	GO:0001880	Mullerian duct regression	IMP	J:89999
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:75084
Biological Process	GO:0051148	negative regulation of muscle cell differentiation	IMP	J:299435
Biological Process	GO:0050768	negative regulation of neurogenesis	IMP	J:124681
Biological Process	GO:0014912	negative regulation of smooth muscle cell migration	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IMP	J:121318
Biological Process	GO:0007399	nervous system development	IMP	J:121318
Biological Process	GO:0014032	neural crest cell development	IMP	J:153961
Biological Process	GO:0021998	neural plate mediolateral regionalization	IMP	J:119568
Biological Process	GO:0060896	neural plate pattern specification	IMP	J:119568
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:97214
Biological Process	GO:0001649	osteoblast differentiation	IDA	J:299402
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:89521
Biological Process	GO:0003148	outflow tract septum morphogenesis	IMP	J:89521
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:119568
Biological Process	GO:0048339	paraxial mesoderm development	IMP	J:119568
Biological Process	GO:0048352	paraxial mesoderm structural organization	IMP	J:119568
Biological Process	GO:0007389	pattern specification process	IMP	J:97214
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:89521
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0021983	pituitary gland development	IMP	J:121318
Biological Process	GO:0021983	pituitary gland development	IMP	J:121318
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:164563
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IMP	J:139945
Biological Process	GO:1904414	positive regulation of cardiac ventricle development	IMP	J:139945
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:106392
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:97214
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:97214
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:97214
Biological Process	GO:1902895	positive regulation of miRNA transcription	IDA	J:169047
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:139945
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:111392
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:152281
Biological Process	GO:0032915	positive regulation of transforming growth factor beta2 production	IMP	J:75084
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	IMP	J:139945
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	IMP	J:89521
Biological Process	GO:2000772	regulation of cellular senescence	IGI	J:190763
Biological Process	GO:0048378	regulation of lateral mesodermal cell fate specification	IGI	J:119568
Biological Process	GO:0060021	roof of mouth development	IMP	J:97214
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:124681
Biological Process	GO:0001756	somitogenesis	IMP	J:119568
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	IEA	J:72247
Biological Process	GO:0003186	tricuspid valve morphogenesis	IMP	J:111392
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	IMP	J:89521
Biological Process	GO:0060412	ventricular septum morphogenesis	IMP	J:75084
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	IMP	J:75084
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	IMP	J:89521

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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