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GO Annotations Graph
Symbol
Name
ID
Pdpk1
3-phosphoinositide dependent protein kinase 1
MGI:1338068

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:00046763-phosphoinositide-dependent protein kinase activityISOJ:155856
Molecular FunctionGO:00046763-phosphoinositide-dependent protein kinase activityIDAJ:53564
Molecular FunctionGO:00046763-phosphoinositide-dependent protein kinase activityISOJ:164563
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005158insulin receptor bindingISOJ:155856
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0016004phospholipase activator activityISOJ:164563
Molecular FunctionGO:0043274phospholipase bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:121227
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0042995cell projectionISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:85182
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0016023cytoplasmic, membrane-bounded vesicleIDAJ:85182
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0097481neuronal postsynaptic densityIDAJ:187362
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0043204perikaryonISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0032148activation of protein kinase B activityISOJ:164563
Biological ProcessGO:0019722calcium-mediated signalingISOJ:164563
Biological ProcessGO:0016477cell migrationISOJ:164563
Biological ProcessGO:0071364cellular response to epidermal growth factor stimulusISOJ:164563
Biological ProcessGO:0032869cellular response to insulin stimulusISOJ:164563
Biological ProcessGO:0007173epidermal growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0097191extrinsic apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0048041focal adhesion assemblyISOJ:155856
Biological ProcessGO:0006972hyperosmotic responseIDAJ:85182
Biological ProcessGO:0035556intracellular signal transductionIBAJ:161428
Biological ProcessGO:0010667negative regulation of cardiac muscle cell apoptotic processIMPJ:150014
Biological ProcessGO:0043524negative regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0006469negative regulation of protein kinase activityISOJ:164563
Biological ProcessGO:0034122negative regulation of toll-like receptor signaling pathwayIMPJ:163291
Biological ProcessGO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayISOJ:164563
Biological ProcessGO:0018105peptidyl-serine phosphorylationIBAJ:161428
Biological ProcessGO:0018107peptidyl-threonine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0090004positive regulation of establishment of protein localization to plasma membraneISOJ:164563
Biological ProcessGO:0010518positive regulation of phospholipase activityISOJ:164563
Biological ProcessGO:0051281positive regulation of release of sequestered calcium ion into cytosolISOJ:164563
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0010594regulation of endothelial cell migrationIMPJ:134712
Biological ProcessGO:0043122regulation of I-kappaB kinase/NF-kappaB signalingISOJ:164563
Biological ProcessGO:0043304regulation of mast cell degranulationIMPJ:178435
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0007165signal transductionTASJ:53564
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0003323type B pancreatic cell developmentIMPJ:153548


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory