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GO Annotations Graph
Symbol
Name
ID
Hdac5
histone deacetylase 5
MGI:1333784

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003682chromatin bindingISOJ:155856
Molecular FunctionGO:0001047core promoter bindingISOJ:164563
Molecular FunctionGO:0001046core promoter sequence-specific DNA bindingIDAJ:158762
Molecular FunctionGO:0004407histone deacetylase activityISOJ:164563
Molecular FunctionGO:0004407histone deacetylase activityTASJ:113927
Molecular FunctionGO:0042826histone deacetylase bindingISOJ:164563
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0032041NAD-dependent histone deacetylase activity (H3-K14 specific)IEAJ:72245
Molecular FunctionGO:0005515protein bindingIPIJ:102395
Molecular FunctionGO:0005515protein bindingIPIJ:114106
Molecular FunctionGO:0005515protein bindingIPIJ:99840
Molecular FunctionGO:0005515protein bindingIPIJ:95385
Molecular FunctionGO:0005515protein bindingIPIJ:72326
Molecular FunctionGO:0005515protein bindingIPIJ:136003
Molecular FunctionGO:0005515protein bindingIPIJ:95385
Molecular FunctionGO:0005515protein bindingIPIJ:64684
Molecular FunctionGO:0033558protein deacetylase activityISOJ:164563
Molecular FunctionGO:0019901protein kinase bindingIPIJ:121892
Molecular FunctionGO:0005080protein kinase C bindingISOJ:164563
Molecular FunctionGO:0070491repressing transcription factor bindingISOJ:164563
Molecular FunctionGO:0001226RNA polymerase II transcription corepressor bindingIPIJ:76061
Molecular FunctionGO:0001085RNA polymerase II transcription factor bindingIPIJ:161725
Molecular FunctionGO:0001025RNA polymerase III transcription factor bindingISOJ:164563
Molecular FunctionGO:0003714transcription corepressor activityIGIJ:99840
Molecular FunctionGO:0003714transcription corepressor activityIDAJ:64684
Molecular FunctionGO:0008134transcription factor bindingISOJ:164563
Molecular FunctionGO:0008134transcription factor bindingIPIJ:172910
Molecular FunctionGO:0008134transcription factor bindingISOJ:155856
Molecular FunctionGO:0008134transcription factor bindingTASJ:113927
Molecular FunctionGO:0044212contributes_to
transcription regulatory region DNA binding
ISOJ:164563
Molecular FunctionGO:0001077transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingIMPJ:158762
Cellular ComponentGO:0005737cytoplasmIDAJ:161038
Cellular ComponentGO:0005737cytoplasmTASJ:113927
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:161038
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:121892
Cellular ComponentGO:0005829cytosolIDAJ:133573
Cellular ComponentGO:0005829cytosolIDAJ:136003
Cellular ComponentGO:0005794Golgi apparatusISOJ:164563
Cellular ComponentGO:0000118histone deacetylase complexTASJ:113927
Cellular ComponentGO:0016604nuclear bodyIDAJ:72326
Cellular ComponentGO:0000790nuclear chromatinIDAJ:76061
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:158762
Cellular ComponentGO:0005634nucleusIDAJ:161038
Cellular ComponentGO:0005634nucleusIDAJ:133573
Cellular ComponentGO:0005634nucleusIDAJ:121892
Cellular ComponentGO:0005634nucleusIDAJ:161038
Cellular ComponentGO:0005634nucleusTASJ:113927
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0043234protein complexISOJ:155856
Cellular ComponentGO:0090571RNA polymerase II transcription repressor complexIDAJ:76061
Biological ProcessGO:0042113B cell activationTASJ:113927
Biological ProcessGO:0030183B cell differentiationTASJ:113927
Biological ProcessGO:0071498cellular response to fluid shear stressIDAJ:158762
Biological ProcessGO:0016568chromatin modificationTASJ:113927
Biological ProcessGO:0007507heart developmentIGIJ:93021
Biological ProcessGO:0016575histone deacetylationISOJ:164563
Biological ProcessGO:0006954inflammatory responseTASJ:113927
Biological ProcessGO:0033555multicellular organismal response to stressIMPJ:132207
Biological ProcessGO:0090051negative regulation of cell migration involved in sprouting angiogenesisISOJ:164563
Biological ProcessGO:0010629negative regulation of gene expressionIMPJ:210206
Biological ProcessGO:0010832negative regulation of myotube differentiationISOJ:164563
Biological ProcessGO:0045668negative regulation of osteoblast differentiationIMPJ:99840
Biological ProcessGO:0045843negative regulation of striated muscle tissue developmentTASJ:113927
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:149882
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:73065
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:95385
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIDAJ:64684
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:99840
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIDAJ:210206
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedTASJ:113927
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedIDAJ:102395
Biological ProcessGO:0007399nervous system developmentTASJ:113927
Biological ProcessGO:0002076osteoblast developmentIMPJ:99840
Biological ProcessGO:2000179positive regulation of neural precursor cell proliferationIMPJ:161725
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISOJ:164563
Biological ProcessGO:2000648positive regulation of stem cell proliferationIMPJ:161725
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIMPJ:158762
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0006476protein deacetylationISOJ:164563
Biological ProcessGO:0040029regulation of gene expression, epigeneticISOJ:164563
Biological ProcessGO:0010830regulation of myotube differentiationIDAJ:121892
Biological ProcessGO:0043393regulation of protein bindingISOJ:164563
Biological ProcessGO:0048742regulation of skeletal muscle fiber developmentIGIJ:127416
Biological ProcessGO:0051153regulation of striated muscle cell differentiationIGIJ:127416
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0061333renal tubule morphogenesisIMPJ:158762
Biological ProcessGO:0042220response to cocaineIMPJ:132207
Biological ProcessGO:0042220response to cocaineIDAJ:132207
Biological ProcessGO:0042493response to drugISOJ:155856
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory