GO Annotations Graph

• Symbol: Pxk
• Name: PX domain containing serine/threonine kinase
• ID: MGI:1289230

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0035091	phosphatidylinositol binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:100471
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:100471
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005769	early endosome	IBA	J:265628
Cellular Component	GO:0031313	extrinsic component of endosome membrane	IBA	J:265628
Cellular Component	GO:0005770	late endosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:100471
Cellular Component	GO:0032991	protein-containing complex	IDA	J:125006
Biological Process	GO:0045022	early endosome to late endosome transport	IBA	J:265628
Biological Process	GO:0008333	endosome to lysosome transport	IBA	J:265628
Biological Process	GO:0006954	inflammatory response	ISO	J:164563
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IEP	J:100471
Biological Process	GO:0032780	negative regulation of ATP-dependent activity	IDA	J:100471
Biological Process	GO:0032780	negative regulation of ATP-dependent activity	IBA	J:265628
Biological Process	GO:0043271	negative regulation of monoatomic ion transport	IDA	J:100471
Biological Process	GO:0043271	negative regulation of monoatomic ion transport	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0006622	protein targeting to lysosome	IBA	J:265628