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GO Annotations Graph
Symbol
Name
ID
Lrp5
low density lipoprotein receptor-related protein 5
MGI:1278315

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0071936coreceptor activity involved in Wnt signaling pathwayISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:141207
Molecular FunctionGO:0005515protein bindingIPIJ:145745
Molecular FunctionGO:0042813Wnt-activated receptor activityIDAJ:75973
Molecular FunctionGO:0017147Wnt-protein bindingIPIJ:75973
Molecular FunctionGO:0017147Wnt-protein bindingISOJ:164563
Cellular ComponentGO:0005783endoplasmic reticulumIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005739mitochondrionIDAJ:86816
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneIBAJ:161428
Cellular ComponentGO:0043235receptor complexISOJ:164563
Cellular ComponentGO:0043235receptor complexIBAJ:161428
Biological ProcessGO:0060612adipose tissue developmentISOJ:164563
Biological ProcessGO:0060612adipose tissue developmentIBAJ:161428
Biological ProcessGO:0060033anatomical structure regressionIMPJ:101493
Biological ProcessGO:0009952anterior/posterior pattern specificationIGIJ:91055
Biological ProcessGO:1902262apoptotic process involved in patterning of blood vesselsIMPJ:101493
Biological ProcessGO:0060348bone developmentIMPJ:164779
Biological ProcessGO:0048539bone marrow developmentISOJ:164563
Biological ProcessGO:0048539bone marrow developmentIBAJ:161428
Biological ProcessGO:0060349bone morphogenesisISOJ:164563
Biological ProcessGO:0046849bone remodelingIMPJ:133196
Biological ProcessGO:0046849bone remodelingIGIJ:111359
Biological ProcessGO:0046849bone remodelingIMPJ:128871
Biological ProcessGO:0046849bone remodelingIMPJ:75973
Biological ProcessGO:0046849bone remodelingIMPJ:116515
Biological ProcessGO:0046849bone remodelingIMPJ:126821
Biological ProcessGO:0046849bone remodelingIGIJ:146078
Biological ProcessGO:0060444branching involved in mammary gland duct morphogenesisIMPJ:115934
Biological ProcessGO:0060070canonical Wnt signaling pathwayIMPJ:115934
Biological ProcessGO:0060070canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0060070canonical Wnt signaling pathwayIDAJ:91019
Biological ProcessGO:0060070canonical Wnt signaling pathwayIDAJ:107732
Biological ProcessGO:0042074cell migration involved in gastrulationIGIJ:91055
Biological ProcessGO:0060764cell-cell signaling involved in mammary gland developmentIMPJ:115934
Biological ProcessGO:0042632cholesterol homeostasisIBAJ:161428
Biological ProcessGO:0042632cholesterol homeostasisISOJ:164563
Biological ProcessGO:0008203cholesterol metabolic processIMPJ:81174
Biological ProcessGO:0042733embryonic digit morphogenesisIGIJ:91055
Biological ProcessGO:0006897endocytosisIEAJ:60000
Biological ProcessGO:0035426extracellular matrix-cell signalingIDAJ:107732
Biological ProcessGO:0001702gastrulation with mouth forming secondIGIJ:91055
Biological ProcessGO:0006007glucose catabolic processISOJ:164563
Biological ProcessGO:0035108limb morphogenesisIGIJ:111359
Biological ProcessGO:0060603mammary gland duct morphogenesisIGIJ:150203
Biological ProcessGO:0007275multicellular organism developmentIEAJ:60000
Biological ProcessGO:0045668negative regulation of osteoblast differentiationISOJ:164563
Biological ProcessGO:0071901negative regulation of protein serine/threonine kinase activityISOJ:164563
Biological ProcessGO:0002076osteoblast developmentIMPJ:164779
Biological ProcessGO:0002076osteoblast developmentIMPJ:116515
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:164563
Biological ProcessGO:0045600positive regulation of fat cell differentiationISOJ:164563
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationISOJ:164563
Biological ProcessGO:0045840positive regulation of mitotic nuclear divisionISOJ:164563
Biological ProcessGO:0033690positive regulation of osteoblast proliferationIMPJ:75973
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIDAJ:107732
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:107732
Biological ProcessGO:0042981regulation of apoptotic processIMPJ:75973
Biological ProcessGO:0008217regulation of blood pressureISOJ:164563
Biological ProcessGO:0046850regulation of bone remodelingIMPJ:111467
Biological ProcessGO:0060828regulation of canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0061178regulation of insulin secretion involved in cellular response to glucose stimulusIMPJ:81174
Biological ProcessGO:0060042retina morphogenesis in camera-type eyeISOJ:164563
Biological ProcessGO:0061299retina vasculature morphogenesis in camera-type eyeIGIJ:154020
Biological ProcessGO:0061299retina vasculature morphogenesis in camera-type eyeIMPJ:75973
Biological ProcessGO:0061299retina vasculature morphogenesis in camera-type eyeIMPJ:135279
Biological ProcessGO:0061304retinal blood vessel morphogenesisISOJ:164563
Biological ProcessGO:0061304retinal blood vessel morphogenesisIBAJ:161428
Biological ProcessGO:0035019somatic stem cell population maintenanceIMPJ:152469
Biological ProcessGO:0001944vasculature developmentIMPJ:101493
Biological ProcessGO:0016055Wnt signaling pathwayIGIJ:99178
Biological ProcessGO:0016055Wnt signaling pathwayIDAJ:75973
Biological ProcessGO:0016055Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0044332Wnt signaling pathway involved in dorsal/ventral axis specificationISOJ:164563
Biological ProcessGO:0044332Wnt signaling pathway involved in dorsal/ventral axis specificationIBAJ:161428


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory