GO Annotations Graph

• Symbol: Slc6a2
• Name: solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
• ID: MGI:1270850

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0043014	alpha-tubulin binding	ISO	J:155856
Molecular Function	GO:0048487	beta-tubulin binding	ISO	J:155856
Molecular Function	GO:0005330	dopamine:sodium symporter activity	ISO	J:164563
Molecular Function	GO:0005330	dopamine:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008504	monoamine transmembrane transporter activity	IMP	J:289076
Molecular Function	GO:0008504	monoamine transmembrane transporter activity	ISO	J:100021
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	IMP	J:289076
Molecular Function	GO:0005328	neurotransmitter:sodium symporter activity	IEA	J:72247
Molecular Function	GO:0005334	norepinephrine:sodium symporter activity	IDA	J:145526
Molecular Function	GO:0005334	norepinephrine:sodium symporter activity	ISO	J:155856
Molecular Function	GO:0005334	norepinephrine:sodium symporter activity	ISO	J:164563
Molecular Function	GO:0005334	norepinephrine:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0032809	neuronal cell body membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098793	presynapse	IDA	J:61825
Cellular Component	GO:0042734	presynaptic membrane	IBA	J:265628
Biological Process	GO:0051583	dopamine uptake involved in synaptic transmission	IBA	J:265628
Biological Process	GO:0015844	monoamine transport	ISO	J:100021
Biological Process	GO:0098810	neurotransmitter reuptake	IDA	J:61825
Biological Process	GO:0098810	neurotransmitter reuptake	IMP	J:61825
Biological Process	GO:0098810	neurotransmitter reuptake	IDA	J:61825
Biological Process	GO:0006836	neurotransmitter transport	IMP	J:289076
Biological Process	GO:0006836	neurotransmitter transport	IDA	J:73988
Biological Process	GO:0015874	norepinephrine transport	ISO	J:155856
Biological Process	GO:0015874	norepinephrine transport	IBA	J:265628
Biological Process	GO:0051620	norepinephrine uptake	IMP	J:289076
Biological Process	GO:0048265	response to pain	IMP	J:73988
Biological Process	GO:0035725	sodium ion transmembrane transport	IBA	J:265628