GO Annotations Graph

• Symbol: Asic2
• Name: acid-sensing ion channel 2
• ID: MGI:1100867

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015280	ligand-gated sodium channel activity	IBA	J:265628
Molecular Function	GO:0015280	ligand-gated sodium channel activity	IDA	J:44171
Molecular Function	GO:0015280	ligand-gated sodium channel activity	IDA	J:68839
Molecular Function	GO:0005261	monoatomic cation channel activity	IMP	J:74681
Molecular Function	GO:0005261	monoatomic cation channel activity	IDA	J:74681
Molecular Function	GO:0005216	monoatomic ion channel activity	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IDA	J:131953
Molecular Function	GO:0022839	monoatomic ion gated channel activity	IDA	J:124264
Molecular Function	GO:0022839	monoatomic ion gated channel activity	IMP	J:124264
Molecular Function	GO:0005515	protein binding	IPI	J:150806
Molecular Function	GO:0005515	protein binding	IPI	J:150806
Molecular Function	GO:0005272	sodium channel activity	IEA	J:72247
Molecular Function	GO:0005272	sodium channel activity	IEA	J:60000
Molecular Function	GO:0005248	voltage-gated sodium channel activity	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IDA	J:150806
Cellular Component	GO:0016020	membrane	IDA	J:44171
Cellular Component	GO:0043005	neuron projection	IDA	J:96521
Cellular Component	GO:0043025	neuronal cell body	IDA	J:96521
Cellular Component	GO:0005886	plasma membrane	IDA	J:74681
Cellular Component	GO:0005886	plasma membrane	IDA	J:68839
Cellular Component	GO:0045202	synapse	IDA	J:150806
Biological Process	GO:0071468	cellular response to acidic pH	ISO	J:155856
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	IMP	J:76712
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:109770
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:124264
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:164935
Biological Process	GO:0051649	establishment of localization in cell	IDA	J:131953
Biological Process	GO:0098655	monoatomic cation transmembrane transport	IDA	J:74681
Biological Process	GO:0006812	monoatomic cation transport	IMP	J:74681
Biological Process	GO:0006812	monoatomic cation transport	IDA	J:74681
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IMP	J:109770
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IMP	J:124264
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IMP	J:164935
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IDA	J:124264
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IDA	J:131953
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:90117
Biological Process	GO:0007602	phototransduction	IMP	J:90117
Biological Process	GO:2001259	positive regulation of cation channel activity	ISO	J:155856
Biological Process	GO:0051965	positive regulation of synapse assembly	IMP	J:150806
Biological Process	GO:0035418	protein localization to synapse	IMP	J:150806
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:164935
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IMP	J:124264
Biological Process	GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	IMP	J:157720
Biological Process	GO:0019229	regulation of vasoconstriction	IMP	J:135644
Biological Process	GO:0010447	response to acidic pH	IMP	J:74681
Biological Process	GO:0010447	response to acidic pH	IDA	J:68839
Biological Process	GO:0010447	response to acidic pH	IDA	J:74681
Biological Process	GO:0009612	response to mechanical stimulus	IMP	J:76712
Biological Process	GO:0007605	sensory perception of sound	IMP	J:96521
Biological Process	GO:0050915	sensory perception of sour taste	ISO	J:164563
Biological Process	GO:0035725	sodium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006814	sodium ion transport	ISO	J:155856
Biological Process	GO:0006814	sodium ion transport	IDA	J:68839
Biological Process	GO:0006814	sodium ion transport	IDA	J:44171
Biological Process	GO:0007416	synapse assembly	IMP	J:150806