GO Annotations Graph

• Symbol: Slc46a1
• Name: solute carrier family 46, member 1
• ID: MGI:1098733

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005542	folic acid binding	IEA	J:60000
Molecular Function	GO:0008517	folic acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0008517	folic acid transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0140211	folic acid:proton symporter activity	IDA	J:127097
Molecular Function	GO:0140211	folic acid:proton symporter activity	ISO	J:164563
Molecular Function	GO:0015232	heme transmembrane transporter activity	IDA	J:122693
Molecular Function	GO:0015350	methotrexate transmembrane transporter activity	IDA	J:127097
Molecular Function	GO:0015078	proton transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015293	symporter activity	ISO	J:164563
Molecular Function	GO:0022857	transmembrane transporter activity	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:122693
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:319976
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:122693
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:1904447	folate import across plasma membrane	IDA	J:127097
Biological Process	GO:1904447	folate import across plasma membrane	ISO	J:164563
Biological Process	GO:0098838	folate transmembrane transport	ISO	J:164563
Biological Process	GO:0015884	folic acid transport	ISO	J:155856
Biological Process	GO:0015884	folic acid transport	ISO	J:164563
Biological Process	GO:0015886	heme transport	IDA	J:122693
Biological Process	GO:1902600	proton transmembrane transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628