GO Annotations Graph

• Symbol: Wasf2
• Name: WASP family, member 2
• ID: MGI:1098641

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0071933	Arp2/3 complex binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:164892
Molecular Function	GO:0005515	protein binding	IPI	J:130482
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0051018	protein kinase A binding	ISO	J:164563
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	IBA	J:265628
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:72247
Cellular Component	GO:0005769	early endosome	IDA	J:81687
Cellular Component	GO:0005622	intracellular anatomical structure	ISO	J:117719
Cellular Component	GO:0030027	lamellipodium	IBA	J:265628
Cellular Component	GO:0030027	lamellipodium	IDA	J:149119
Cellular Component	GO:0030027	lamellipodium	ISO	J:117719
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0001726	ruffle	IDA	J:81687
Cellular Component	GO:0031209	SCAR complex	ISO	J:164563
Cellular Component	GO:0031209	SCAR complex	IDA	J:302461
Cellular Component	GO:0031209	SCAR complex	IBA	J:265628
Cellular Component	GO:0045202	synapse	EXP	J:263402
Cellular Component	GO:0045202	synapse	IDA	J:263402
Biological Process	GO:0030036	actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:84642
Biological Process	GO:0030048	actin filament-based movement	IMP	J:84642
Biological Process	GO:0001667	ameboidal-type cell migration	IMP	J:84651
Biological Process	GO:0001525	angiogenesis	IMP	J:84651
Biological Process	GO:0006897	endocytosis	IDA	J:81687
Biological Process	GO:0030032	lamellipodium assembly	IMP	J:84651
Biological Process	GO:0072673	lamellipodium morphogenesis	IMP	J:149119
Biological Process	GO:0035855	megakaryocyte development	IMP	J:149119
Biological Process	GO:0051497	negative regulation of stress fiber assembly	ISO	J:164563
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	IBA	J:265628
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0099173	postsynapse organization	IMP	J:263380
Biological Process	GO:0099173	postsynapse organization	IDA	J:263380
Biological Process	GO:0099173	postsynapse organization	IDA	J:263380
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IMP	J:263380
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:263380
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:263380
Biological Process	GO:0016601	Rac protein signal transduction	IMP	J:84642