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GO Annotations Graph
Symbol
Name
ID
Alox8
arachidonate 8-lipoxygenase
MGI:1098228

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:00185591,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00348271,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185571,2-dihydroxyfluorene 1,1-alpha-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185661,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185612'-aminobiphenyl-2,3-diol 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185562,2',3-trihydroxybiphenyl dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185422,3-dihydroxy DDT 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185632,3-dihydroxy-ethylbenzene 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185712,3-dihydroxy-p-cumate dioxygenase activityIEAJ:72245
Molecular FunctionGO:00349552,3-dihydroxydiphenyl ether dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185742,6-dichloro-p-hydroquinone 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185732-aminophenol 1,6-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00348342-mercaptobenzothiazole dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185623,4-dihydroxyfluorene 4,4-alpha-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185683,4-dihydroxyphenanthrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185723,5-dichlorocatechol 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00348033-hydroxy-2-naphthoate 2,3-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00348104,5-dihydroxybenzo(a)pyrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:00349224,5-dihydroxypyrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:00349364,6-dichloro-3-methylcatechol 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00470744-hydroxycatechol 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:00185585,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activityIEAJ:72245
Molecular FunctionGO:00345435-aminosalicylate dioxygenase activityIEAJ:72245
Molecular FunctionGO:00348147,8-dihydroxy benzo(a)pyrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:00348129,10-dihydroxybenzo(a)pyrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:0050473arachidonate 15-lipoxygenase activityISOJ:164563
Molecular FunctionGO:0050473arachidonate 15-lipoxygenase activityISOJ:155856
Molecular FunctionGO:0047677arachidonate 8(R)-lipoxygenase activityIEAJ:72245
Molecular FunctionGO:0036403arachidonate 8(S)-lipoxygenase activityIDAJ:200515
Molecular FunctionGO:0034806benzo(a)pyrene 11,12-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0034808benzo(a)pyrene 4,5-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0034813benzo(a)pyrene 7,8-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0034811benzo(a)pyrene 9,10-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0005509calcium ion bindingISOJ:164563
Molecular FunctionGO:0018564carbazole 1,9a-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0019114catechol dioxygenase activityIEAJ:72245
Molecular FunctionGO:0018575chlorocatechol 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0018565dihydroxydibenzothiophene dioxygenase activityIEAJ:72245
Molecular FunctionGO:0019117dihydroxyfluorene dioxygenase activityIEAJ:72245
Molecular FunctionGO:0051213dioxygenase activityIEAJ:60000
Molecular FunctionGO:0034956diphenyl ether 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0018569hydroquinone 1,2-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0005506iron ion bindingISOJ:164563
Molecular FunctionGO:0016165linoleate 13S-lipoxygenase activityISOJ:164563
Molecular FunctionGO:0008289lipid bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:72247
Molecular FunctionGO:0016491oxidoreductase activityIEAJ:60000
Molecular FunctionGO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenIEAJ:72247
Molecular FunctionGO:0018570p-cumate 2,3-dioxygenase activityIEAJ:72245
Molecular FunctionGO:0018555phenanthrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:0034934phenanthrene-4-carboxylate dioxygenase activityIEAJ:72245
Molecular FunctionGO:0018560protocatechuate 3,4-dioxygenase type II activityIEAJ:72245
Molecular FunctionGO:0034920pyrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:0034895pyridine-3,4-diol dioxygenase activityIEAJ:72245
Molecular FunctionGO:0018567styrene dioxygenase activityIEAJ:72245
Molecular FunctionGO:0034935tetrachlorobenzene dioxygenase activityIEAJ:72245
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005856cytoskeletonISOJ:164563
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0019898extrinsic component of membraneISOJ:164563
Cellular ComponentGO:0005622intracellularISOJ:164563
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0019369arachidonic acid metabolic processIDAJ:43206
Biological ProcessGO:0019369arachidonic acid metabolic processISOJ:164563
Biological ProcessGO:0019369arachidonic acid metabolic processISOJ:155856
Biological ProcessGO:0051122hepoxilin biosynthetic processISOJ:155856
Biological ProcessGO:0043651linoleic acid metabolic processIDAJ:43206
Biological ProcessGO:0006629lipid metabolic processIEAJ:60000
Biological ProcessGO:0019372lipoxygenase pathwayISOJ:155856
Biological ProcessGO:0019372lipoxygenase pathwayIDAJ:43206
Biological ProcessGO:0045786negative regulation of cell cycleISOJ:164563
Biological ProcessGO:0008285negative regulation of cell proliferationISOJ:164563
Biological ProcessGO:0045926negative regulation of growthISOJ:164563
Biological ProcessGO:0055114oxidation-reduction processIEAJ:60000
Biological ProcessGO:0055114oxidation-reduction processIEAJ:72247
Biological ProcessGO:0090197positive regulation of chemokine secretionISOJ:164563
Biological ProcessGO:0045618positive regulation of keratinocyte differentiationIMPJ:133831
Biological ProcessGO:0010744positive regulation of macrophage derived foam cell differentiationISOJ:164563
Biological ProcessGO:0035360positive regulation of peroxisome proliferator activated receptor signaling pathwayIMPJ:133831


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/02/2021
MGI 6.16
The Jackson Laboratory